Safety and Immunogenicity of a New Rotavirus-Inactivated Vaccine in the Chinese Adolescent Population: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.

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Title: Safety and Immunogenicity of a New Rotavirus-Inactivated Vaccine in the Chinese Adolescent Population: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.
Authors: Liu Y; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Feng G; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., Wu J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Liu X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Pu J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Wang Y; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., You W; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., Yin N; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Yi S; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Tan J; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., Lin X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Huang L; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., Gao J; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Yu Q; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Tong Q; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Zhang Y; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Chen R; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Hu X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Ye J; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Kuang X; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Zhou Y; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China., Hu Z; National Institutes for Food and Drug Control, Beijing 102629, China.; State Key Laboratory of Drug Regulatory Science, Beijing 102629, China., Zhao D; Henan Center for Disease Control and Prevention, Zhenzhou 450016, China., Li H; Institute of Medical Biology, Chinese Academy of Medical Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Disease, Kunming 650118, China.
Source: Vaccines [Vaccines (Basel)] 2025 Mar 30; Vol. 13 (4). Date of Electronic Publication: 2025 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2076-393X
DOI:10.3390/vaccines13040369