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Outcomes of brexucabtagene autoleucel in patients with relapsed/refractory acute lymphoblastic leukemia with CNS involvement.

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Title: Outcomes of brexucabtagene autoleucel in patients with relapsed/refractory acute lymphoblastic leukemia with CNS involvement.
Authors: Muhsen IN; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX., Roloff GW; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL., Faramand R; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Othman T; Division of Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA., Valtis Y; Department of Hematology and Oncology, Memorial Sloan Kettering Cancer Institute, New York City, NY., Kopmar NE; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA., Dekker SE; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA., Connor M; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA., Mercadal S; Transplant and Cellular Therapy Program, Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT., O'Connor TE; Division of Hematology/Oncology, Loyola University Medical Center, Maywood, IL., Dykes KC; Division of Hematology and Oncology, Department of Medicine, University of California San Diego, La Jolla, CA., Ahmed M; Department of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, CA., Jeyakumar N; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA., Zhang A; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA., Miller K; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA., Sutherland KC; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA., Guzowski C; Blood and Marrow Transplant Program, Northside Hospital Cancer Institute, Atlanta, GA., Gupta VK; Division of Hematology & Oncology, University of California Los Angeles, Los Angeles, CA., Majhail N; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer Institute, HCA Healthcare, Nashville, TN., Battiwalla M; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer Institute, HCA Healthcare, Nashville, TN., Solh MM; Blood and Marrow Transplant Program, Northside Hospital Cancer Institute, Atlanta, GA., Malik SA; Center for Blood Cancer and Oncology, Texas Transplant Institute, Austin, TX., Mathews J; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer, Dallas, TX., Oliai CH; Division of Hematology & Oncology, University of California Los Angeles, Los Angeles, CA., Shaughnessy P; Department of Transplant and Cellular Therapy, Sarah Cannon Transplant and Cellular Therapy Program at Methodist Hospital, San Antonio, TX., Mountjoy L; Department of Lymphoma, Colorado Blood Cancer Institute, Denver, CO., Lee CJ; Transplant and Cellular Therapy Program, Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT., Logan AC; Division of Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA., Tsai SB; Division of Hematology/Oncology, Loyola University Medical Center, Maywood, IL., Leonard JT; Division of Hematology-Oncology, Oregon Health & Science University, Portland, OR., Schwartz M; Department of Hematology and Oncology, University of Colorado, Aurora, CO., Sasine JP; Department of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, CA., Kumaran M; Department of Hematology and Oncology, University of Arkansas for Medical Sciences, Little Rock, AR., Frey N; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA., Park JH; Department of Hematology and Oncology, Memorial Sloan Kettering Cancer Institute, New York City, NY., Koura D; Division of Hematology and Oncology, Department of Medicine, University of California San Diego, La Jolla, CA., Cassaday RD; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA., Shah BD; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Aldoss I; Division of Leukemia, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA., Muffly LS; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA., Hill LC; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX.
Source: Blood advances [Blood Adv] 2025 Aug 26; Vol. 9 (16), pp. 4081-4089.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Outcomes of brexucabtagene autoleucel in patients with relapsed/refractory acute lymphoblastic leukemia with CNS involvement.
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  Data: <searchLink fieldCode="AU" term="%22Muhsen+IN%22">Muhsen IN</searchLink>; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Roloff+GW%22">Roloff GW</searchLink>; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Faramand+R%22">Faramand R</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Othman+T%22">Othman T</searchLink>; Division of Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Valtis+Y%22">Valtis Y</searchLink>; Department of Hematology and Oncology, Memorial Sloan Kettering Cancer Institute, New York City, NY.<br /><searchLink fieldCode="AU" term="%22Kopmar+NE%22">Kopmar NE</searchLink>; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Dekker+SE%22">Dekker SE</searchLink>; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Connor+M%22">Connor M</searchLink>; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Mercadal+S%22">Mercadal S</searchLink>; Transplant and Cellular Therapy Program, Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22O'Connor+TE%22">O'Connor TE</searchLink>; Division of Hematology/Oncology, Loyola University Medical Center, Maywood, IL.<br /><searchLink fieldCode="AU" term="%22Dykes+KC%22">Dykes KC</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of California San Diego, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Ahmed+M%22">Ahmed M</searchLink>; Department of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Jeyakumar+N%22">Jeyakumar N</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Zhang+A%22">Zhang A</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Miller+K%22">Miller K</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Sutherland+KC%22">Sutherland KC</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Guzowski+C%22">Guzowski C</searchLink>; Blood and Marrow Transplant Program, Northside Hospital Cancer Institute, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Gupta+VK%22">Gupta VK</searchLink>; Division of Hematology & Oncology, University of California Los Angeles, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Majhail+N%22">Majhail N</searchLink>; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer Institute, HCA Healthcare, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Battiwalla+M%22">Battiwalla M</searchLink>; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer Institute, HCA Healthcare, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Solh+MM%22">Solh MM</searchLink>; Blood and Marrow Transplant Program, Northside Hospital Cancer Institute, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Malik+SA%22">Malik SA</searchLink>; Center for Blood Cancer and Oncology, Texas Transplant Institute, Austin, TX.<br /><searchLink fieldCode="AU" term="%22Mathews+J%22">Mathews J</searchLink>; Department of Transplant and Cellular Therapy, Sarah Cannon Cancer, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Oliai+CH%22">Oliai CH</searchLink>; Division of Hematology & Oncology, University of California Los Angeles, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Shaughnessy+P%22">Shaughnessy P</searchLink>; Department of Transplant and Cellular Therapy, Sarah Cannon Transplant and Cellular Therapy Program at Methodist Hospital, San Antonio, TX.<br /><searchLink fieldCode="AU" term="%22Mountjoy+L%22">Mountjoy L</searchLink>; Department of Lymphoma, Colorado Blood Cancer Institute, Denver, CO.<br /><searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Transplant and Cellular Therapy Program, Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Logan+AC%22">Logan AC</searchLink>; Division of Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Tsai+SB%22">Tsai SB</searchLink>; Division of Hematology/Oncology, Loyola University Medical Center, Maywood, IL.<br /><searchLink fieldCode="AU" term="%22Leonard+JT%22">Leonard JT</searchLink>; Division of Hematology-Oncology, Oregon Health & Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Schwartz+M%22">Schwartz M</searchLink>; Department of Hematology and Oncology, University of Colorado, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Sasine+JP%22">Sasine JP</searchLink>; Department of Hematology and Oncology, Cedars-Sinai Medical Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Kumaran+M%22">Kumaran M</searchLink>; Department of Hematology and Oncology, University of Arkansas for Medical Sciences, Little Rock, AR.<br /><searchLink fieldCode="AU" term="%22Frey+N%22">Frey N</searchLink>; Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Department of Hematology and Oncology, Memorial Sloan Kettering Cancer Institute, New York City, NY.<br /><searchLink fieldCode="AU" term="%22Koura+D%22">Koura D</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of California San Diego, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Cassaday+RD%22">Cassaday RD</searchLink>; Division of Hematology and Oncology, Department of Medicine, Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Shah+BD%22">Shah BD</searchLink>; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Aldoss+I%22">Aldoss I</searchLink>; Division of Leukemia, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Muffly+LS%22">Muffly LS</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Hill+LC%22">Hill LC</searchLink>; Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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