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Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours.

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Title: Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours.
Authors: Luskin AT; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA.; Laboratory of Neural Dynamics and Cognition, The Rockefeller University, New York, NY, USA., Li L; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA., Fu X; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Martin MM; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA., Barcomb K; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA., Girven KS; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA., Blackburn T; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA., Wells BA; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA., Thai ST; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA., Li EM; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Psychology, University of Washington, Seattle, WA, USA., Rana AN; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA., Simon RC; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA., Sun L; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA.; TopoGene Inc., Seattle, WA, USA., Gao L; Department of Biochemistry, University of Washington, Seattle, WA, USA., Murry AD; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biological Structure, University of Washington, Seattle, WA, USA., Golden SA; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biological Structure, University of Washington, Seattle, WA, USA., Stuber GD; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA., Ford CP; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA., Gu L; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Bruchas MR; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Department of Pharmacology, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Department of Bioengineering, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.
Source: Nature [Nature] 2025 Jul; Vol. 643 (8071), pp. 437-447. Date of Electronic Publication: 2025 May 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours.
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  Data: <searchLink fieldCode="AU" term="%22Luskin+AT%22">Luskin AT</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA.; Laboratory of Neural Dynamics and Cognition, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Fu+X%22">Fu X</searchLink>; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Martin+MM%22">Martin MM</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Barcomb+K%22">Barcomb K</searchLink>; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Girven+KS%22">Girven KS</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Blackburn+T%22">Blackburn T</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wells+BA%22">Wells BA</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Thai+ST%22">Thai ST</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Li+EM%22">Li EM</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Psychology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rana+AN%22">Rana AN</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Simon+RC%22">Simon RC</searchLink>; 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Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biological Structure, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Stuber+GD%22">Stuber GD</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ford+CP%22">Ford CP</searchLink>; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Gu+L%22">Gu L</searchLink>; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bruchas+MR%22">Bruchas MR</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Department of Pharmacology, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.; Department of Bioengineering, University of Washington, Seattle, WA, USA. mbruchas@uw.edu.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Jul; Vol. 643 (8071), pp. 437-447. <i>Date of Electronic Publication: </i>2025 May 07.
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