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Consensus and controversies about diagnosing GH deficiency: a Delphi survey by the GH research society.

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Title: Consensus and controversies about diagnosing GH deficiency: a Delphi survey by the GH research society.
Authors: Arlien-Søborg MC; Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark., Radovick S; Department of Pediatrics, Rutgers University-Robert Wood Johnson Medical School New, Brunswick, NJ, USA., Boguszewski MCS; Department of Pediatrics, Federal University of Parana, Curitiba, Brazil., Bidlingmaier M; Department of Medicine IV, LMU University Hospital, LMU Munich, München, Germany., Johannsson G; Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden.; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Grimberg A; Division of Endocrinology and Diabetes, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA., Ho KKY; Garvan Institute of Medical Research and St. Vincent's Hospital, Sydney, NSW, Australia., Biller BMK; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Choong CS; Department of Endocrinology, Perth Children's Hospital & School of Medicine, University of Western Australia, Crawley, WA, Australia., Hoffman AR; Department of Medicine, Stanford University, Stanford, CA, USA., Backeljauw P; Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA., Boguszewski CL; Endocrine Division (SEMPR), Department of Internal Medicine, Federal University of Parana, Curitiba, Brazil., Bollerslev J; Faculty of Medicine, University of Oslo, Oslo, Norway., Brue T; Department of Endocrinology, Conception University Hospital, Marseille, France., Chanson P; Service d'Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l'Hypophyse, Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France., Christ E; Department of Endocrinology, Diabetology and Metabolism and Endocrine and Neuroendocrine Tumor Center, University Hospital of Basel, Basel, Switzerland., Cianfarani S; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.; Endocrinology and Diabetes Unit, I.R.C.C.S. 'Bambino Gesù' Children's Hospital, Rome, Italy., Clayton PE; Developmental Biology & Medicine, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK., Cohen P; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Dauber A; Division of Endocrinology, Children's National Hospital, Washington, DC, USA., Fleseriu M; Departments of Medicine and Neurological Surgery, Pituitary Center, Oregon Health Sciences University, Portland, OR, USA., Gebauer J; Department of Internal Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany., Giustina A; Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy., Higham CE; Department of Endocrinology, Christie Hospital NHS Foundation Trust and Division of Cancer Sciences,, University of Manchester, Manchester, UK., Horikawa R; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan., Höybye C; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden., Juul A; Department of Growth and Reproduction-Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Lodish M; University of California, San Francisco, CA, USA., Luo X; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Mauras N; Nemours Children's Health Jacksonville, Jacksonville, FL, USA., Miller KK; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Melmed S; Pituitary Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Neggers SJCMM; Erasmus University Medical Centre, Rotterdam, The Netherlands., Karavitaki N; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK.; Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Rosenfeld R; Department of Pediatrics, Oregon Health Science University, Portland, OR, USA., Ross R; University of Sheffield, Sheffield, UK., Savendahl L; Division of Pediatric Endocrinology, Karolinska University Hospital, Stockholm, Sweden., Schilbach K; Department of Medicine IV, LMU University Hospital, LMU Munich, München, Germany., Collett-Solberg PF; Discipline of Endocrinology, Internal Medicine Department, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil., Strasburger CJ; Charité Universitätsmedizin, Berlin, Germany., Tritos NA; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., van Santen HM; Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center and Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Yuen KCJ; Department of Neuroendocrinology, St. Joseph's Hospital and Medical Center, University of Arizona College of Medicine and Creighton School of Medicine, Phoenix, AZ, USA., Jorgensen JOL; Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark. joj@clin.au.dk.
Source: Pituitary [Pituitary] 2025 May 07; Vol. 28 (3), pp. 57. Date of Electronic Publication: 2025 May 07.
Publication Type: Journal Article; Review; Consensus Statement
Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: United States NLM ID: 9814578 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7403 (Electronic) Linking ISSN: 1386341X NLM ISO Abbreviation: Pituitary Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Consensus and controversies about diagnosing GH deficiency: a Delphi survey by the GH research society.
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  Data: <searchLink fieldCode="AU" term="%22Arlien-Søborg+MC%22">Arlien-Søborg MC</searchLink>; Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Radovick+S%22">Radovick S</searchLink>; Department of Pediatrics, Rutgers University-Robert Wood Johnson Medical School New, Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Boguszewski+MCS%22">Boguszewski MCS</searchLink>; Department of Pediatrics, Federal University of Parana, Curitiba, Brazil.<br /><searchLink fieldCode="AU" term="%22Bidlingmaier+M%22">Bidlingmaier M</searchLink>; Department of Medicine IV, LMU University Hospital, LMU Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Johannsson+G%22">Johannsson G</searchLink>; Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden.; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Grimberg+A%22">Grimberg A</searchLink>; Division of Endocrinology and Diabetes, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Ho+KKY%22">Ho KKY</searchLink>; Garvan Institute of Medical Research and St. Vincent's Hospital, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Biller+BMK%22">Biller BMK</searchLink>; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Choong+CS%22">Choong CS</searchLink>; Department of Endocrinology, Perth Children's Hospital & School of Medicine, University of Western Australia, Crawley, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Hoffman+AR%22">Hoffman AR</searchLink>; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Backeljauw+P%22">Backeljauw P</searchLink>; Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.<br /><searchLink fieldCode="AU" term="%22Boguszewski+CL%22">Boguszewski CL</searchLink>; Endocrine Division (SEMPR), Department of Internal Medicine, Federal University of Parana, Curitiba, Brazil.<br /><searchLink fieldCode="AU" term="%22Bollerslev+J%22">Bollerslev J</searchLink>; Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Brue+T%22">Brue T</searchLink>; Department of Endocrinology, Conception University Hospital, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Chanson+P%22">Chanson P</searchLink>; Service d'Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l'Hypophyse, Université Paris-Saclay, Inserm, Physiologie et Physiopathologie Endocriniennes, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Christ+E%22">Christ E</searchLink>; Department of Endocrinology, Diabetology and Metabolism and Endocrine and Neuroendocrine Tumor Center, University Hospital of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cianfarani+S%22">Cianfarani S</searchLink>; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.; Endocrinology and Diabetes Unit, I.R.C.C.S. 'Bambino Gesù' Children's Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Clayton+PE%22">Clayton PE</searchLink>; Developmental Biology & Medicine, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Cohen+P%22">Cohen P</searchLink>; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dauber+A%22">Dauber A</searchLink>; Division of Endocrinology, Children's National Hospital, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Fleseriu+M%22">Fleseriu M</searchLink>; Departments of Medicine and Neurological Surgery, Pituitary Center, Oregon Health Sciences University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Gebauer+J%22">Gebauer J</searchLink>; Department of Internal Medicine, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Giustina+A%22">Giustina A</searchLink>; Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Higham+CE%22">Higham CE</searchLink>; Department of Endocrinology, Christie Hospital NHS Foundation Trust and Division of Cancer Sciences,, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Horikawa+R%22">Horikawa R</searchLink>; Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Höybye+C%22">Höybye C</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Juul+A%22">Juul A</searchLink>; Department of Growth and Reproduction-Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lodish+M%22">Lodish M</searchLink>; University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Luo+X%22">Luo X</searchLink>; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Mauras+N%22">Mauras N</searchLink>; Nemours Children's Health Jacksonville, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Miller+KK%22">Miller KK</searchLink>; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Melmed+S%22">Melmed S</searchLink>; Pituitary Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Neggers+SJCMM%22">Neggers SJCMM</searchLink>; Erasmus University Medical Centre, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Karavitaki+N%22">Karavitaki N</searchLink>; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK.; Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+R%22">Rosenfeld R</searchLink>; Department of Pediatrics, Oregon Health Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Ross+R%22">Ross R</searchLink>; University of Sheffield, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Savendahl+L%22">Savendahl L</searchLink>; Division of Pediatric Endocrinology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Schilbach+K%22">Schilbach K</searchLink>; Department of Medicine IV, LMU University Hospital, LMU Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Collett-Solberg+PF%22">Collett-Solberg PF</searchLink>; Discipline of Endocrinology, Internal Medicine Department, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Strasburger+CJ%22">Strasburger CJ</searchLink>; Charité Universitätsmedizin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Tritos+NA%22">Tritos NA</searchLink>; Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22van+Santen+HM%22">van Santen HM</searchLink>; Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center and Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yuen+KCJ%22">Yuen KCJ</searchLink>; Department of Neuroendocrinology, St. Joseph's Hospital and Medical Center, University of Arizona College of Medicine and Creighton School of Medicine, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Jorgensen+JOL%22">Jorgensen JOL</searchLink>; Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark. joj@clin.au.dk.
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