Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis.

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Title: Impaired CAMK4 Activity Limits Atherosclerosis and Reprograms Myelopoiesis.
Authors: Gonzalez AL; Department of Pathology, Microbiology, and Immunology (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.), Vanderbilt University, Nashville, TN., Youwakim CM; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Leake BF; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Fuller KK; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Rahman SMJ; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Dungan MM; Department of Pathology, Microbiology, and Immunology (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.), Vanderbilt University, Nashville, TN., Gu K; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Bonin JL; Department of Immunology and Microbiology, Albany Medical College, NY (J.L.B., K.C.M.)., Cavnar AB; Department of Pathology, Microbiology, and Immunology (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.), Vanderbilt University, Nashville, TN., Michell DL; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Davison LM; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Cutchins C; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Chu YE; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Hematology and Oncology (Y.E.C., P.B.F.), Vanderbilt University Medical Center, Nashville, TN., Yuan S; Department of Pharmacology and Chemical Biology, University of Pittsburgh, PA (S.Y.)., Yurdagul A Jr; Department of Molecular and Cellular Physiology (A.Y.), LSU Health Sciences Center-Shreveport, LA., Traylor JG; Department of Pathology and Translational Pathobiology (J.G.T., A.W.O.), LSU Health Sciences Center-Shreveport, LA., Orr AW; Department of Pathology and Translational Pathobiology (J.G.T., A.W.O.), LSU Health Sciences Center-Shreveport, LA., Kohutek ZA; Department of Radiation Oncology (Z.A.K.), Vanderbilt University Medical Center, Nashville, TN., Linton MF; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., MacNamara KC; Department of Immunology and Microbiology, Albany Medical College, NY (J.L.B., K.C.M.)., Ferrell PB; Vanderbilt Institute for Infection, Immunology, and Inflammation (P.B.F., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Hematology and Oncology (Y.E.C., P.B.F.), Vanderbilt University Medical Center, Nashville, TN., Vickers KC; Department of Pathology, Microbiology, and Immunology (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Molecular Physiology and Biophysics (K.C.V., J.D.B., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Madhur MS; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis (M.S.M.)., Brown JD; Department of Molecular Physiology and Biophysics (K.C.V., J.D.B., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN., Doran AC; Department of Pathology, Microbiology, and Immunology (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Molecular Physiology and Biophysics (K.C.V., J.D.B., A.C.D.), Vanderbilt University, Nashville, TN.; Vanderbilt Institute for Infection, Immunology, and Inflammation (P.B.F., A.C.D.), Vanderbilt University, Nashville, TN.; Department of Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., Y.E.C., M.F.L., P.B.F., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.; Division of Cardiovascular Medicine (C.M.Y., B.F.L., K.K.F., S.M.J.R., K.G., D.L.M., L.M.D., C.C., M.F.L., K.C.V., J.D.B., A.C.D.), Vanderbilt University Medical Center, Nashville, TN.
Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Jul; Vol. 45 (7), pp. e286-e306. Date of Electronic Publication: 2025 May 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4636
DOI:10.1161/ATVBAHA.125.322530