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Mapping administration route-dependent transduction profiles of commonly used AAV variants in mice by barcode amplicon sequencing.

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Title: Mapping administration route-dependent transduction profiles of commonly used AAV variants in mice by barcode amplicon sequencing.
Authors: Abele S; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Alanis-Lobato G; Global Computational Biology & Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Oti M; Global Computational Biology & Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Rust W; Global Computational Biology & Digital Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Blazevic D; Eye Health & Research Beyond Borders, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Danner-Liskus J; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Mayer C; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Zimmermann G; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Zuckschwerdt K; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Schönberger T; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Gross P; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Lempp C; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Michelfelder S; Eye Health & Research Beyond Borders, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany., Strobel B; Global Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach, Germany.
Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Apr 14; Vol. 33 (2), pp. 101468. Date of Electronic Publication: 2025 Apr 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2329-0501
DOI:10.1016/j.omtm.2025.101468