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Versatile Imidazole Scaffold with Potent Activity against Multiple Apicomplexan Parasites.

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Title: Versatile Imidazole Scaffold with Potent Activity against Multiple Apicomplexan Parasites.
Authors: Khim M; Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington 98109, United States.; Center for Global Infectious Disease ResearchSeattle Children's Research Institute, Seattle, Washington 98109, United States., Montgomery J; Divisions of Infectious Diseases and ResearchVA Portland Healthcare System, Portland, Oregon 97239, United States., Laureano De Souza M; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, United States., Delvillar M; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, United States., Weible LJ; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Reemerging Infectious DiseasesUniversity of Washington, Seattle, Washington 98109, United States., Prabakaran M; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Reemerging Infectious DiseasesUniversity of Washington, Seattle, Washington 98109, United States., Hulverson MA; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Reemerging Infectious DiseasesUniversity of Washington, Seattle, Washington 98109, United States., Eck T; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life SciencesMontclair State University, Montclair, New Jersey 07043, United States., Bheemanabonia RY; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life SciencesMontclair State University, Montclair, New Jersey 07043, United States., Alday PH; Divisions of Infectious Diseases and ResearchVA Portland Healthcare System, Portland, Oregon 97239, United States.; Division of Infectious Diseases,Oregon Health & Science University School of Medicine, Portland, Oregon 97239, United States., Rotella DP; Department of Chemistry and Biochemistry and Sokol Institute of Pharmaceutical Life SciencesMontclair State University, Montclair, New Jersey 07043, United States., Doggett JS; Divisions of Infectious Diseases and ResearchVA Portland Healthcare System, Portland, Oregon 97239, United States.; Division of Infectious Diseases,Oregon Health & Science University School of Medicine, Portland, Oregon 97239, United States., Staker BL; Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington 98109, United States.; Center for Global Infectious Disease ResearchSeattle Children's Research Institute, Seattle, Washington 98109, United States., Ojo KK; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Reemerging Infectious DiseasesUniversity of Washington, Seattle, Washington 98109, United States.; Department of Global HealthUniversity of Washington, Seattle, Washington 98195, United States., Bhanot P; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, United States.
Source: ACS infectious diseases [ACS Infect Dis] 2025 Jun 13; Vol. 11 (6), pp. 1497-1507. Date of Electronic Publication: 2025 May 08.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
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