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Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling.

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Title: Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling.
Authors: Mia S; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Siokatas G; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece., Sidiropoulou R; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Hoffman M; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA., Fragkiadakis K; Cardiology Department, Heraklion University General Hospital, Crete, Greece., Markopoulou E; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA., Elesawy MI; Department of Immunology and Pathology, Washington University in St. Louis, St. Louis, MO, USA; Divison of Cardiology, Washington University in St. Louis, St. Louis, MO, USA., Roy R; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA., Blair S; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Kuwabara Y; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Rapushi E; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Chaudhuri D; Division of Cardiovascular Medicine, Department of Internal Medicine, Biochemistry, Biomedical Engineering, University of Utah, Salt Lake City, UT, USA., Makarewich CA; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Gao E; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA., Koch WJ; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA., Schilling JD; Department of Immunology and Pathology, Washington University in St. Louis, St. Louis, MO, USA; Divison of Cardiology, Washington University in St. Louis, St. Louis, MO, USA., Molkentin JD; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Marketou M; Cardiology Department, Heraklion University General Hospital, Crete, Greece., Drosatos K; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: k.drosatos@uc.edu.
Source: Cell reports. Medicine [Cell Rep Med] 2025 Jun 17; Vol. 6 (6), pp. 102125. Date of Electronic Publication: 2025 May 07.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling.
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  Data: <searchLink fieldCode="AU" term="%22Mia+S%22">Mia S</searchLink>; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Siokatas+G%22">Siokatas G</searchLink>; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Department of Genetics, Development and Molecular Biology, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Sidiropoulou+R%22">Sidiropoulou R</searchLink>; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Hoffman+M%22">Hoffman M</searchLink>; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fragkiadakis+K%22">Fragkiadakis K</searchLink>; Cardiology Department, Heraklion University General Hospital, Crete, Greece.<br /><searchLink fieldCode="AU" term="%22Markopoulou+E%22">Markopoulou E</searchLink>; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Elesawy+MI%22">Elesawy MI</searchLink>; Department of Immunology and Pathology, Washington University in St. Louis, St. Louis, MO, USA; Divison of Cardiology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Roy+R%22">Roy R</searchLink>; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Blair+S%22">Blair S</searchLink>; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kuwabara+Y%22">Kuwabara Y</searchLink>; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Rapushi+E%22">Rapushi E</searchLink>; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+D%22">Chaudhuri D</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, Biochemistry, Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Makarewich+CA%22">Makarewich CA</searchLink>; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Gao+E%22">Gao E</searchLink>; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Koch+WJ%22">Koch WJ</searchLink>; Center for Translational Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schilling+JD%22">Schilling JD</searchLink>; Department of Immunology and Pathology, Washington University in St. Louis, St. Louis, MO, USA; Divison of Cardiology, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Molkentin+JD%22">Molkentin JD</searchLink>; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Marketou+M%22">Marketou M</searchLink>; Cardiology Department, Heraklion University General Hospital, Crete, Greece.<br /><searchLink fieldCode="AU" term="%22Drosatos+K%22">Drosatos K</searchLink>; Metabolic Biology Laboratory, Cardiovascular Center, Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: k.drosatos@uc.edu.
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