Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy.
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| Title: | Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy. |
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| Authors: | Wang C; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. chao.wang@moffitt.org., Yu X; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Teer JK; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Yao J; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Du D; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Liu X; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Thompson ZJ; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Wang MH; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Welsh EA; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Memon D; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Chan TA; Center for Immunotherapy and Precision Immuno-oncology, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA., Makarov V; Center for Immunotherapy and Precision Immuno-oncology, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA., Anadon CM; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Integrative Immunobiology, Duke School of Medicine, Durham, NC, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA., Saeed L; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Boyle TA; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Fang B; Proteomics & Metabolomics Core Facility, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Koomen JM; Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Cox C; Immune and Cellular Therapy Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Landin AM; Immune and Cellular Therapy Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Yoder SJ; Molecular Genomics Core Facility, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Kim S; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Radiation Oncology, Immunology, Cancer Biology, Mayo Clinic Alix College of Medicine & Health Sciences, Jacksonville, FL, USA., Chen DT; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Pilon-Thomas SA; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Conejo-Garcia JR; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Integrative Immunobiology, Duke School of Medicine, Durham, NC, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA., Antonia SJ; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA., Haura EB; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA., Creelan BC; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. ben.creelan@moffitt.org.; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. ben.creelan@moffitt.org. |
| Source: | Nature cancer [Nat Cancer] 2025 May; Vol. 6 (5), pp. 801-819. Date of Electronic Publication: 2025 May 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40341231 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. chao.wang@moffitt.org.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Teer+JK%22">Teer JK</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Yao+J%22">Yao J</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Du+D%22">Du D</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+ZJ%22">Thompson ZJ</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wang+MH%22">Wang MH</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Welsh+EA%22">Welsh EA</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Memon+D%22">Memon D</searchLink>; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Chan+TA%22">Chan TA</searchLink>; Center for Immunotherapy and Precision Immuno-oncology, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Makarov+V%22">Makarov V</searchLink>; Center for Immunotherapy and Precision Immuno-oncology, Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Anadon+CM%22">Anadon CM</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Integrative Immunobiology, Duke School of Medicine, Durham, NC, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Saeed+L%22">Saeed L</searchLink>; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Boyle+TA%22">Boyle TA</searchLink>; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Fang+B%22">Fang B</searchLink>; Proteomics & Metabolomics Core Facility, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Koomen+JM%22">Koomen JM</searchLink>; Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Cox+C%22">Cox C</searchLink>; Immune and Cellular Therapy Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Landin+AM%22">Landin AM</searchLink>; Immune and Cellular Therapy Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Yoder+SJ%22">Yoder SJ</searchLink>; Molecular Genomics Core Facility, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Radiation Oncology, Immunology, Cancer Biology, Mayo Clinic Alix College of Medicine & Health Sciences, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Chen+DT%22">Chen DT</searchLink>; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pilon-Thomas+SA%22">Pilon-Thomas SA</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Conejo-Garcia+JR%22">Conejo-Garcia JR</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.; Department of Integrative Immunobiology, Duke School of Medicine, Durham, NC, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Antonia+SJ%22">Antonia SJ</searchLink>; Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Haura+EB%22">Haura EB</searchLink>; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Creelan+BC%22">Creelan BC</searchLink>; Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. ben.creelan@moffitt.org.; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. ben.creelan@moffitt.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2025 May; Vol. 6 (5), pp. 801-819. <i>Date of Electronic Publication: </i>2025 May 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101761119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-1347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226621347%22">26621347 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40341231 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s43018-025-00946-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 801 Titles: – TitleFull: Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang C – PersonEntity: Name: NameFull: Yu X – PersonEntity: Name: NameFull: Teer JK – PersonEntity: Name: NameFull: Yao J – PersonEntity: Name: NameFull: Du D – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Thompson ZJ – PersonEntity: Name: NameFull: Wang MH – PersonEntity: Name: NameFull: Welsh EA – PersonEntity: Name: NameFull: Memon D – PersonEntity: Name: NameFull: Chan TA – PersonEntity: Name: NameFull: Makarov V – PersonEntity: Name: NameFull: Anadon CM – PersonEntity: Name: NameFull: Saeed L – PersonEntity: Name: NameFull: Boyle TA – PersonEntity: Name: NameFull: Fang B – PersonEntity: Name: NameFull: Koomen JM – PersonEntity: Name: NameFull: Cox C – PersonEntity: Name: NameFull: Landin AM – PersonEntity: Name: NameFull: Yoder SJ – PersonEntity: Name: NameFull: Kim S – PersonEntity: Name: NameFull: Chen DT – PersonEntity: Name: NameFull: Pilon-Thomas SA – PersonEntity: Name: NameFull: Conejo-Garcia JR – PersonEntity: Name: NameFull: Antonia SJ – PersonEntity: Name: NameFull: Haura EB – PersonEntity: Name: NameFull: Creelan BC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2025 May Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2662-1347 Numbering: – Type: volume Value: 6 – Type: issue Value: 5 Titles: – TitleFull: Nature cancer Type: main |
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