JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine.
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| Title: | JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine. |
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| Authors: | Ahn JH; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kim J; HK inno.N Corporation, Seoul, Republic of Korea.; Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea., Kwak J; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim J; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee NY; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea., Choi H; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Bae HJ; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho SH; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Jung SG; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon HM; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon E; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kim D; HK inno.N Corporation, Seoul, Republic of Korea., Kim M; HK inno.N Corporation, Seoul, Republic of Korea., Yoon D; HK inno.N Corporation, Seoul, Republic of Korea., Kim S; HK inno.N Corporation, Seoul, Republic of Korea., Kim B; HK inno.N Corporation, Seoul, Republic of Korea., Kang BC; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2025 Oct; Vol. 182 (20), pp. 5071-5082. Date of Electronic Publication: 2025 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40341986 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.; Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwak+J%22">Kwak J</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+NY%22">Lee NY</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+HJ%22">Bae HJ</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+SH%22">Cho SH</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+SG%22">Jung SG</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+HM%22">Kwon HM</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+E%22">Kwon E</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+D%22">Yoon D</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; HK inno.N Corporation, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+BC%22">Kang BC</searchLink>; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2025 Oct; Vol. 182 (20), pp. 5071-5082. <i>Date of Electronic Publication: </i>2025 May 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40341986 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/bph.70055 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5071 Titles: – TitleFull: JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ahn JH – PersonEntity: Name: NameFull: Kim J – PersonEntity: Name: NameFull: Kwak J – PersonEntity: Name: NameFull: Kim J – PersonEntity: Name: NameFull: Lee NY – PersonEntity: Name: NameFull: Choi H – PersonEntity: Name: NameFull: Bae HJ – PersonEntity: Name: NameFull: Cho SH – PersonEntity: Name: NameFull: Jung SG – PersonEntity: Name: NameFull: Kwon HM – PersonEntity: Name: NameFull: Kwon E – PersonEntity: Name: NameFull: Kim D – PersonEntity: Name: NameFull: Kim M – PersonEntity: Name: NameFull: Yoon D – PersonEntity: Name: NameFull: Kim S – PersonEntity: Name: NameFull: Kim B – PersonEntity: Name: NameFull: Kang BC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2025 Oct Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1476-5381 Numbering: – Type: volume Value: 182 – Type: issue Value: 20 Titles: – TitleFull: British journal of pharmacology Type: main |
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