Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.
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| Title: | Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality. |
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| Authors: | Cunningham CE; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Vizeacoumar FS; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Zhang Y; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Kyrylenko L; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Both S; Department of Pharmacy, Pharmaceutical Biology, Saarland University, PharmaScienceHub, 66123 Saarbrücken, Germany., Maranda V; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Dong H; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Price JDW; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Gao P; Global Institute for Food Security, University of Saskatchewan, Saskatoon, SK S7N 4L8, Canada; Agriculture and Agri-Food Canada, Saskatoon Research and Development Centre, 107 Science Place, Saskatoon, SK S7N 0X2, Canada., Wagner K; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany., Wu Y; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany., Lazell-Wright M; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Ganapathysamy A; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Hari R; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Bhanumathy KK; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Denomy C; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Saxena A; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Vizeacoumar JP; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Morales AM; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Khan F; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Mosley S; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada., Chen A; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada., Katrii T; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Zoller BGE; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany., Rajamanickam K; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Walke P; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, and Cameco MS Neuroscience Research Centre, 701 Queen St., Saskatoon, SK S7K 0M7, Canada., Gong L; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Patel H; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Elhasasna H; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Dahiya R; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Abuhussein O; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Dmitriev A; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Freywald T; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Munhoz EP; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Ruppin E; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Bioinformatics and Computational Biology and Department of Computer Sciences, University of Maryland, College Park, MD 20742, USA., Lee JS; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Bioinformatics and Computational Biology and Department of Computer Sciences, University of Maryland, College Park, MD 20742, USA; Department of Precision Medicine, School of Medicine and Department of Artificial Intelligence, Sungkyunkwan University, Suwon 16419, Republic of Korea., Rox K; Department of Chemical Biology (CBIO), Helmholtz Center for Infection Research (HZI), Inhoffenstrasse 7, 38124 Braunschweig, Germany., Koebel M; Department of Pathology, University of Calgary, Calgary, AB, Canada., Hopkins L; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Lee CH; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada., Yadav S; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Gasparoni G; Department of Genetics, Saarland University, Saarbrücken, Germany., Walter J; Department of Genetics, Saarland University, Saarbrücken, Germany., Krishnan A; Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, and Cameco MS Neuroscience Research Centre, 701 Queen St., Saskatoon, SK S7K 0M7, Canada., Datla R; Global Institute for Food Security, University of Saskatchewan, Saskatoon, SK S7N 4L8, Canada., Toosi B; Western College of Veterinary Medicine, University of Saskatchewan, Room 2343, 52 Campus Drive, Saskatoon S7N 5B4, Canada., Baker K; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada., Meens J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Cescon DW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Ailles L; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Leary SC; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Wu Y; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Empting M; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany. Electronic address: martin.empting@helmholtz-hips.de., Kiemer AK; Department of Pharmacy, Pharmaceutical Biology, Saarland University, PharmaScienceHub, 66123 Saarbrücken, Germany; Center for Gender-Specific Biology and Medicine (CGBM), 66421 Homburg, Germany. Electronic address: pharm.bio.kiemer@uni-saarland.de., Freywald A; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada. Electronic address: andrew.freywald@usask.ca., Vizeacoumar FJ; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Cancer Research, Saskatchewan Cancer Agency, 107 Wiggins Road, Saskatoon, SK S7N 5E5, Canada. Electronic address: franco.vizeacoumar@usask.ca. |
| Source: | Cell genomics [Cell Genom] 2025 Jun 11; Vol. 5 (6), pp. 100876. Date of Electronic Publication: 2025 May 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40347943 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cunningham+CE%22">Cunningham CE</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Vizeacoumar+FS%22">Vizeacoumar FS</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Kyrylenko+L%22">Kyrylenko L</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Both+S%22">Both S</searchLink>; Department of Pharmacy, Pharmaceutical Biology, Saarland University, PharmaScienceHub, 66123 Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Maranda+V%22">Maranda V</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Dong+H%22">Dong H</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Price+JDW%22">Price JDW</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Gao+P%22">Gao P</searchLink>; Global Institute for Food Security, University of Saskatchewan, Saskatoon, SK S7N 4L8, Canada; Agriculture and Agri-Food Canada, Saskatoon Research and Development Centre, 107 Science Place, Saskatoon, SK S7N 0X2, Canada.<br /><searchLink fieldCode="AU" term="%22Wagner+K%22">Wagner K</searchLink>; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Lazell-Wright+M%22">Lazell-Wright M</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Ganapathysamy+A%22">Ganapathysamy A</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Hari+R%22">Hari R</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Bhanumathy+KK%22">Bhanumathy KK</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Denomy+C%22">Denomy C</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Saxena+A%22">Saxena A</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Vizeacoumar+JP%22">Vizeacoumar JP</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Morales+AM%22">Morales AM</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Khan+F%22">Khan F</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Mosley+S%22">Mosley S</searchLink>; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.<br /><searchLink fieldCode="AU" term="%22Katrii+T%22">Katrii T</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Zoller+BGE%22">Zoller BGE</searchLink>; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Rajamanickam+K%22">Rajamanickam K</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Walke+P%22">Walke P</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, and Cameco MS Neuroscience Research Centre, 701 Queen St., Saskatoon, SK S7K 0M7, Canada.<br /><searchLink fieldCode="AU" term="%22Gong+L%22">Gong L</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Patel+H%22">Patel H</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Elhasasna+H%22">Elhasasna H</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Dahiya+R%22">Dahiya R</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Abuhussein+O%22">Abuhussein O</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Dmitriev+A%22">Dmitriev A</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Freywald+T%22">Freywald T</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Munhoz+EP%22">Munhoz EP</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Ruppin+E%22">Ruppin E</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Bioinformatics and Computational Biology and Department of Computer Sciences, University of Maryland, College Park, MD 20742, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Center for Bioinformatics and Computational Biology and Department of Computer Sciences, University of Maryland, College Park, MD 20742, USA; Department of Precision Medicine, School of Medicine and Department of Artificial Intelligence, Sungkyunkwan University, Suwon 16419, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Rox+K%22">Rox K</searchLink>; Department of Chemical Biology (CBIO), Helmholtz Center for Infection Research (HZI), Inhoffenstrasse 7, 38124 Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Koebel+M%22">Koebel M</searchLink>; Department of Pathology, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Hopkins+L%22">Hopkins L</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Yadav+S%22">Yadav S</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Gasparoni+G%22">Gasparoni G</searchLink>; Department of Genetics, Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Walter+J%22">Walter J</searchLink>; Department of Genetics, Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Krishnan+A%22">Krishnan A</searchLink>; Department of Anatomy, Physiology, and Pharmacology, University of Saskatchewan, and Cameco MS Neuroscience Research Centre, 701 Queen St., Saskatoon, SK S7K 0M7, Canada.<br /><searchLink fieldCode="AU" term="%22Datla+R%22">Datla R</searchLink>; Global Institute for Food Security, University of Saskatchewan, Saskatoon, SK S7N 4L8, Canada.<br /><searchLink fieldCode="AU" term="%22Toosi+B%22">Toosi B</searchLink>; Western College of Veterinary Medicine, University of Saskatchewan, Room 2343, 52 Campus Drive, Saskatoon S7N 5B4, Canada.<br /><searchLink fieldCode="AU" term="%22Baker+K%22">Baker K</searchLink>; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.<br /><searchLink fieldCode="AU" term="%22Meens+J%22">Meens J</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Cescon+DW%22">Cescon DW</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ailles+L%22">Ailles L</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Leary+SC%22">Leary SC</searchLink>; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.<br /><searchLink fieldCode="AU" term="%22Empting+M%22">Empting M</searchLink>; Antiviral & Antivirulence Drugs (AVID), Helmholtz Institute for Pharmaceutical Research, Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany. Electronic address: martin.empting@helmholtz-hips.de.<br /><searchLink fieldCode="AU" term="%22Kiemer+AK%22">Kiemer AK</searchLink>; Department of Pharmacy, Pharmaceutical Biology, Saarland University, PharmaScienceHub, 66123 Saarbrücken, Germany; Center for Gender-Specific Biology and Medicine (CGBM), 66421 Homburg, Germany. Electronic address: pharm.bio.kiemer@uni-saarland.de.<br /><searchLink fieldCode="AU" term="%22Freywald+A%22">Freywald A</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada. Electronic address: andrew.freywald@usask.ca.<br /><searchLink fieldCode="AU" term="%22Vizeacoumar+FJ%22">Vizeacoumar FJ</searchLink>; Department of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada; Cancer Research, Saskatchewan Cancer Agency, 107 Wiggins Road, Saskatoon, SK S7N 5E5, Canada. Electronic address: franco.vizeacoumar@usask.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229918284260106676%22">Cell genomics</searchLink> [Cell Genom] 2025 Jun 11; Vol. 5 (6), pp. 100876. <i>Date of Electronic Publication: </i>2025 May 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918284260106676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-979X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222666979X%22">2666979X </searchLink><i>NLM ISO Abbreviation: </i>Cell Genom <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.xgen.2025.100876 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 100876 Titles: – TitleFull: Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cunningham CE – PersonEntity: Name: NameFull: Vizeacoumar FS – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Kyrylenko L – PersonEntity: Name: NameFull: Both S – PersonEntity: Name: NameFull: Maranda V – PersonEntity: Name: NameFull: Dong H – PersonEntity: Name: NameFull: Price JDW – PersonEntity: Name: NameFull: Gao P – PersonEntity: Name: NameFull: Wagner K – PersonEntity: Name: NameFull: Wu Y – PersonEntity: Name: NameFull: Lazell-Wright M – PersonEntity: Name: NameFull: Ganapathysamy A – PersonEntity: Name: NameFull: Hari R – PersonEntity: Name: NameFull: Bhanumathy KK – PersonEntity: Name: NameFull: Denomy C – PersonEntity: Name: NameFull: Saxena A – PersonEntity: Name: NameFull: Vizeacoumar JP – PersonEntity: Name: NameFull: Morales AM – PersonEntity: Name: NameFull: Khan F – PersonEntity: Name: NameFull: Mosley S – PersonEntity: Name: NameFull: Chen A – PersonEntity: Name: NameFull: Katrii T – PersonEntity: Name: NameFull: Zoller BGE – PersonEntity: Name: NameFull: Rajamanickam K – PersonEntity: Name: NameFull: Walke P – PersonEntity: Name: NameFull: Gong L – PersonEntity: Name: NameFull: Patel H – PersonEntity: Name: NameFull: Elhasasna H – PersonEntity: Name: NameFull: Dahiya R – PersonEntity: Name: NameFull: Abuhussein O – PersonEntity: Name: NameFull: Dmitriev A – PersonEntity: Name: NameFull: Freywald T – PersonEntity: Name: NameFull: Munhoz EP – PersonEntity: Name: NameFull: Ruppin E – PersonEntity: Name: NameFull: Lee JS – PersonEntity: Name: NameFull: Rox K – PersonEntity: Name: NameFull: Koebel M – PersonEntity: Name: NameFull: Hopkins L – PersonEntity: Name: NameFull: Lee CH – PersonEntity: Name: NameFull: Yadav S – PersonEntity: Name: NameFull: Gasparoni G – PersonEntity: Name: NameFull: Walter J – PersonEntity: Name: NameFull: Krishnan A – PersonEntity: Name: NameFull: Datla R – PersonEntity: Name: NameFull: Toosi B – PersonEntity: Name: NameFull: Baker K – PersonEntity: Name: NameFull: Meens J – PersonEntity: Name: NameFull: Cescon DW – PersonEntity: Name: NameFull: Ailles L – PersonEntity: Name: NameFull: Leary SC – PersonEntity: Name: NameFull: Wu Y – PersonEntity: Name: NameFull: Empting M – PersonEntity: Name: NameFull: Kiemer AK – PersonEntity: Name: NameFull: Freywald A – PersonEntity: Name: NameFull: Vizeacoumar FJ IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 06 Text: 2025 Jun 11 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2666-979X Numbering: – Type: volume Value: 5 – Type: issue Value: 6 Titles: – TitleFull: Cell genomics Type: main |
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