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RNA transcripts serve as a template for double-strand break repair in human cells.

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Title: RNA transcripts serve as a template for double-strand break repair in human cells.
Authors: Jalan M; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brambati A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shah H; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, Cornell University, New York, NY, USA., McDermott N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Patel J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zhu Y; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Doymaz A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, Cornell University, New York, NY, USA., Wu J; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; SUNY Downstate Health Sciences University, New York, NY, USA., Anderson KS; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gazzo A; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pareja F; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Yamaguchi TN; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, CA, USA., Vougiouklakis T; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ahmed-Seghir S; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Steinberg P; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA., Neiman-Golden A; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA., Azeroglu B; Laboratory of Genome Integrity, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA., Gomez-Aguilar J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., da Silva EM; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hussain S; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Higginson D; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Boutros PC; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, CA, USA.; Department of Urology, University of California, Los Angeles, CA, USA.; Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA., Riaz N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Reis-Filho JS; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; AstraZeneca, Gaithersburg, MD, USA., Powell SN; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. powells@mskcc.org.; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. powells@mskcc.org., Sfeir A; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. sfeira@mskcc.org.
Source: Nature communications [Nat Commun] 2025 May 10; Vol. 16 (1), pp. 4349. Date of Electronic Publication: 2025 May 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: RNA transcripts serve as a template for double-strand break repair in human cells.
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  Data: <searchLink fieldCode="AU" term="%22Jalan+M%22">Jalan M</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Brambati+A%22">Brambati A</searchLink>; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shah+H%22">Shah H</searchLink>; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, Cornell University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22McDermott+N%22">McDermott N</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Patel+J%22">Patel J</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Doymaz+A%22">Doymaz A</searchLink>; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Medicine, Cornell University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; SUNY Downstate Health Sciences University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+KS%22">Anderson KS</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gazzo+A%22">Gazzo A</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pareja+F%22">Pareja F</searchLink>; 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Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Azeroglu+B%22">Azeroglu B</searchLink>; Laboratory of Genome Integrity, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gomez-Aguilar+J%22">Gomez-Aguilar J</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22da+Silva+EM%22">da Silva EM</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hussain+S%22">Hussain S</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Higginson+D%22">Higginson D</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Boutros+PC%22">Boutros PC</searchLink>; Department of Human Genetics, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, CA, USA.; Department of Urology, University of California, Los Angeles, CA, USA.; Broad Stem Cell Research Center, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Riaz+N%22">Riaz N</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Reis-Filho+JS%22">Reis-Filho JS</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Powell+SN%22">Powell SN</searchLink>; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. powells@mskcc.org.; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. powells@mskcc.org.<br /><searchLink fieldCode="AU" term="%22Sfeir+A%22">Sfeir A</searchLink>; Molecular Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. sfeira@mskcc.org.
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