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Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat.

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Title: Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat.
Authors: Zanichelli A; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.; UO di Medicina, Centro Angioedema, I.R.C.C.S. Policlinico San Donato, Milano, Italy., Cattaneo D; Unit of Clinical Pathology, Luigi Sacco University Hospital, Milan, Italy., Gidaro A; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy., Senter R; Department of Systems Medicine, University Hospital of Padua, Padua, Italy., Arcoleo F; UOC di Patologia Clinica e Immunologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy., Accardo P; UOC di Patologia Clinica e Immunologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy., Bignardi D; Allergology Unit, IRCCS San Martino Polyclinic Hospital, Genoa, Italy., Borrelli P; SSD Dermatologia e Allergologia, Ospedale Beauregard, Aosta, Italy., Colangelo C; Allergy and Clinical Immunology Unit, Azienda Sanitaria Locale Di Pescara, Pescara, Italy., De Pasquale T; Department of Allergology, University Hospital 'Maggiore della Carità' of Novara, Novara, Italy., Firinu D; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Perego F; Department of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS, Milan, Italy., Triggiani M; Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy., Spadaro G; Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy., Cogliati C; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy., Bizzi E; Internal Medicine Department, Fatebenefratelli and Sacco Hospitals, Milan, Italy., Popescu Janu V; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy., Guarino MD; Allergy Unit, Hospital of Civitanova Marche, Civitanova Marche, Italy., Quattrocchi P; Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy., Brussino L; Allergy and Clinical Immunology Unit, Department of Medical Sciences, University of Torino and Mauriziano Hospital, Torino, Italy., Rossi O; Immunoallergology Unit, University Hospital of Careggi, Florence, Italy., Triggianese P; Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Roma Tor Vergata, Rome, Italy., Agolini S; Department of Clinical Immunology, Azienda Ospedaliera Universitaria Ospedali Riuniti di Ancona, Ancona, Italy., Giardino F; Internal Medicine Unit, Azienda Ospedaliero-Universitaria Policlinico 'G.Rodolico-San Marco', Catania, Italy., Montinaro V; U.O.C. di Nefrologia e Dialisi, Ospedale Generale Regionale 'F. Miulli', Acquaviva delle Fonti (BA), Italy., Cancian M; Department of Systems Medicine, University Hospital of Padua, Padua, Italy.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Apr 25; Vol. 16, pp. 1550133. Date of Electronic Publication: 2025 Apr 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Assessment of potential drug-drug interactions in patients with hereditary angioedema from the ITACA cohort: simulations from a real-life dataset considering danazol versus berotralstat.
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  Data: <searchLink fieldCode="AU" term="%22Zanichelli+A%22">Zanichelli A</searchLink>; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.; UO di Medicina, Centro Angioedema, I.R.C.C.S. Policlinico San Donato, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Cattaneo+D%22">Cattaneo D</searchLink>; Unit of Clinical Pathology, Luigi Sacco University Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gidaro+A%22">Gidaro A</searchLink>; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Senter+R%22">Senter R</searchLink>; Department of Systems Medicine, University Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Arcoleo+F%22">Arcoleo F</searchLink>; UOC di Patologia Clinica e Immunologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Accardo+P%22">Accardo P</searchLink>; UOC di Patologia Clinica e Immunologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Bignardi+D%22">Bignardi D</searchLink>; Allergology Unit, IRCCS San Martino Polyclinic Hospital, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Borrelli+P%22">Borrelli P</searchLink>; SSD Dermatologia e Allergologia, Ospedale Beauregard, Aosta, Italy.<br /><searchLink fieldCode="AU" term="%22Colangelo+C%22">Colangelo C</searchLink>; Allergy and Clinical Immunology Unit, Azienda Sanitaria Locale Di Pescara, Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22De+Pasquale+T%22">De Pasquale T</searchLink>; Department of Allergology, University Hospital 'Maggiore della Carità' of Novara, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Firinu+D%22">Firinu D</searchLink>; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Perego+F%22">Perego F</searchLink>; Department of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Triggiani+M%22">Triggiani M</searchLink>; Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Spadaro+G%22">Spadaro G</searchLink>; Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Cogliati+C%22">Cogliati C</searchLink>; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bizzi+E%22">Bizzi E</searchLink>; Internal Medicine Department, Fatebenefratelli and Sacco Hospitals, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Popescu+Janu+V%22">Popescu Janu V</searchLink>; Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Guarino+MD%22">Guarino MD</searchLink>; Allergy Unit, Hospital of Civitanova Marche, Civitanova Marche, Italy.<br /><searchLink fieldCode="AU" term="%22Quattrocchi+P%22">Quattrocchi P</searchLink>; Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Brussino+L%22">Brussino L</searchLink>; Allergy and Clinical Immunology Unit, Department of Medical Sciences, University of Torino and Mauriziano Hospital, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+O%22">Rossi O</searchLink>; Immunoallergology Unit, University Hospital of Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Triggianese+P%22">Triggianese P</searchLink>; Rheumatology, Allergology and Clinical Immunology, Department of Systems Medicine, University of Roma Tor Vergata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Agolini+S%22">Agolini S</searchLink>; Department of Clinical Immunology, Azienda Ospedaliera Universitaria Ospedali Riuniti di Ancona, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Giardino+F%22">Giardino F</searchLink>; Internal Medicine Unit, Azienda Ospedaliero-Universitaria Policlinico 'G.Rodolico-San Marco', Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Montinaro+V%22">Montinaro V</searchLink>; U.O.C. di Nefrologia e Dialisi, Ospedale Generale Regionale 'F. Miulli', Acquaviva delle Fonti (BA), Italy.<br /><searchLink fieldCode="AU" term="%22Cancian+M%22">Cancian M</searchLink>; Department of Systems Medicine, University Hospital of Padua, Padua, Italy.
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