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Altered GIP/GLP-1 Secretion Ratio is Associated With Impaired β Cell Function in Humans.

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Title: Altered GIP/GLP-1 Secretion Ratio is Associated With Impaired β Cell Function in Humans.
Authors: Di Giuseppe G; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Gliozzo G; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Ciccarelli G; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Carciero L; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Brunetti M; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Soldovieri L; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Quero G; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Digestive Surgery Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy., Cinti F; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Nista EC; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy., De Lucia SS; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy., Gasbarrini A; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy., Alfieri S; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Digestive Surgery Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy., Pontecorvi A; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Mari A; Institute of Neuroscience, National Research Council, 2-35122 Padua, Italy., Hartmann B; Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Holst JJ; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark., Giaccari A; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy., Mezza T; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy.
Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2025 Dec 18; Vol. 111 (1), pp. e240-e246.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Altered GIP/GLP-1 Secretion Ratio is Associated With Impaired β Cell Function in Humans.
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  Data: <searchLink fieldCode="AU" term="%22Di+Giuseppe+G%22">Di Giuseppe G</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gliozzo+G%22">Gliozzo G</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ciccarelli+G%22">Ciccarelli G</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Carciero+L%22">Carciero L</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Brunetti+M%22">Brunetti M</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Soldovieri+L%22">Soldovieri L</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Quero+G%22">Quero G</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Digestive Surgery Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cinti+F%22">Cinti F</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Nista+EC%22">Nista EC</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22De+Lucia+SS%22">De Lucia SS</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gasbarrini+A%22">Gasbarrini A</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Alfieri+S%22">Alfieri S</searchLink>; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Digestive Surgery Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pontecorvi+A%22">Pontecorvi A</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mari+A%22">Mari A</searchLink>; Institute of Neuroscience, National Research Council, 2-35122 Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Hartmann+B%22">Hartmann B</searchLink>; Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Holst+JJ%22">Holst JJ</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Giaccari+A%22">Giaccari A</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mezza+T%22">Mezza T</searchLink>; Endocrinology and Diabetology Unit, University Hospital Agostino Gemelli, 00168 Rome, Italy.; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, 00168 Rome, Italy.; Pancreas Unit, Digestive Diseases Center, University Hospital Agostino Gemelli, 00168 Rome, Italy.
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