An integrated transcriptomic cell atlas of human endoderm-derived organoids.

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Bibliographic Details
Title: An integrated transcriptomic cell atlas of human endoderm-derived organoids.
Authors: Xu Q; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. quan.xu@roche.com., Halle L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Hediyeh-Zadeh S; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Life Sciences, Technical University of Munich, Munich, Germany., Kuijs M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Riedweg R; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Kilik U; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland., Recaldin T; Roche Innovation Center Basel, Roche Pharma Research and Early Development, Basel, Switzerland., Yu Q; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Rall I; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Frum T; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA., Adam L; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Parikh S; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Life Sciences, Technical University of Munich, Munich, Germany., Kfuri-Rubens R; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; IIIrd Medical Department, Klinikum rechts der Isar, Munich, Germany.; School of Medicine, Technical University of Munich, Munich, Germany., Gander M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Klein D; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Curion F; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., He Z; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Fleck JS; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Oost K; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Kahnwald M; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Barbiero S; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Mitrofanova O; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Maciag GJ; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark., Jensen KB; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark., Lutolf M; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Liberali P; Biozentrum, University of Basel, Basel, Switzerland.; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Spence JR; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan College of Engineering, Ann Arbor, MI, USA., Gjorevski N; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Beumer J; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch., Theis FJ; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Life Sciences, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de., Camp JG; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.
Source: Nature genetics [Nat Genet] 2025 May; Vol. 57 (5), pp. 1201-1212. Date of Electronic Publication: 2025 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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