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Safety, Pharmacokinetics, and Pharmacodynamics of a 6-h N,N-Dimethyltryptamine (DMT) Infusion in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Trial.

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Title: Safety, Pharmacokinetics, and Pharmacodynamics of a 6-h N,N-Dimethyltryptamine (DMT) Infusion in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Trial.
Authors: van der Heijden KV; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden University Medical Centre, Leiden, the Netherlands., Zuiker RGJA; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden University Medical Centre, Leiden, the Netherlands., Otto ME; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Bryan CS; Algernon Pharmaceuticals, Vancouver, Canada., Stewart N; Clinical Development Solutions, Winnipeg, Canada., Stillwell C; Algernon Pharmaceuticals, Vancouver, Canada., De Kam ML; Centre for Human Drug Research, Leiden, the Netherlands., van Leuken MB; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., van Gerven JMA; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden University Medical Centre, Leiden, the Netherlands., Jacobs GE; Centre for Human Drug Research, Leiden, the Netherlands.; Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands.
Source: Clinical and translational science [Clin Transl Sci] 2025 May; Vol. 18 (5), pp. e70234.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, Pharmacokinetics, and Pharmacodynamics of a 6-h N,N-Dimethyltryptamine (DMT) Infusion in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Trial.
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              Text: 2025 May
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