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Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in acute lymphoblastic leukemia.

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Title: Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in acute lymphoblastic leukemia.
Authors: Saorin A; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Dehler A; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Galvan B; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Steffen F; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Ray M; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Lu D; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX., Yu X; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX., Kim J; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Drakul A; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Kisele S; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Wang J; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Bourquin JP; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland., Bornhauser BC; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.
Source: Blood [Blood] 2025 Aug 14; Vol. 146 (7), pp. 861-873.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
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  Data: Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in acute lymphoblastic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Saorin+A%22">Saorin A</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dehler+A%22">Dehler A</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Galvan+B%22">Galvan B</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Steffen+F%22">Steffen F</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ray+M%22">Ray M</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lu+D%22">Lu D</searchLink>; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Drakul+A%22">Drakul A</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kisele+S%22">Kisele S</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Bourquin+JP%22">Bourquin JP</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bornhauser+BC%22">Bornhauser BC</searchLink>; Department of Oncology and Children's Research Centre, University Children's Hospital Zürich, Zürich, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2025 Aug 14; Vol. 146 (7), pp. 861-873.
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              Text: 2025 Aug 14
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