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Natural history, immunological and genetic characteristics of preclinical inflammatory bowel disease (EARLY): study protocol for a prospective cohort study.

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Title: Natural history, immunological and genetic characteristics of preclinical inflammatory bowel disease (EARLY): study protocol for a prospective cohort study.
Authors: Rodríguez-Lago I; Gastroenterology Department, Hospital Universitario de Galdakao, Biobizkaia Health Research Institute, Galdakao 48960, Spain., Marigorta UM; Integrative Genomics Laboratory, CIC bioGUNE, Derio, Spain., Mateos B; Integrative Genomics Laboratory, CIC bioGUNE, Derio, Spain., Mañosa M; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Márquez-Mosquera L; Servei de Aparell Digestiu, Hospital del Mar; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Menchén L; Gastroenterology Department, Hospital General Universitario e Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.; Departamento de Medicina, Universidad Complutense, Madrid, Spain., Rodríguez-Moranta F; Gastroenterology Department, Hospital Universitario Bellvitge, IDIBELL, Hospitalet Llobregat, Barcelona, Spain., Alonso I; Gastroenterology Department, Hospital Universitario de Canarias, La Laguna, Spain., Aguas M; Gastroenterology Department, Hospital Politécnico y Universitario de la Fe, Valencia, Spain., Alonso-Galán H; Gastroenterology Department, Hospital Universitario Donostia, BioGiopuzkoa Health Research Institute, Donostia, Spain., Borràs P; Gastroenterology Department, Hospital Universitari Mútua Terrassa, Terrassa, Spain., Castro B; Gastroenterology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain., Domènech E; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain., Ferreiro-Iglesias R; Gastroenterology Department, Hospital Clínico Universitario de Santiago de Compostela, FIDIS, Santiago de Compostela, Spain., de Francisco R; Gastroenterology Department, Hospital Universitario Central de Asturias, Oviedo, Spain., García-Alonso FJ; Gastroenterology Department, Hospital Universitario Río Hortega, Valladolid, Spain., García N; Gastroenterology Department, Hospital Álvaro Cunqueiro, Vigo, Spain., García-Bosch O; Gastroenterology Department, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Spain., Gargallo C; Gastroenterology Department, Hospital Universitario Lozano Blesa, Zaragoza, Spain., Gisbert JP; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), Madrid, Spain., Iglesias E; Gastroenterology Department, Hospital Universitario Reina Sofía, Córdoba, Spain., Mesonero F; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain., Ortiz de Zárate J; Gastroenterology Department, Hospital Universitario de Basurto, Bilbao, Spain., Ramos L; Gastroenterology Department, Hospital Universitario de Canarias, La Laguna, Spain., Sáinz E; Gastroenterology Department, Hospital Universitari de Manresa, Manresa, Spain., Ladrón P; Gastroenterology Department, Hospital Universitario de Burgos, Burgos, Spain., Suria C; Gastroenterology Department, Hospital Clínico Universitario de Valencia, Valencia, Spain., Ferrer CS; Gastroenterology Department, Hospital Universitario la Paz, Madrid, Spain., Tejido C; Gastroenterology Department, Complejo Hospitalario de Ourense, Ourense, Spain., Varela P; Gastroenterology Department, Hospital Universitario de Cabueñes, Gijón, Spain., Vicente R; Gastroenterology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain., Zabana Y; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitari Mútua Terrassa, Terrassa, Spain., Castany G; GETECCU, Spain., Rodríguez E; GETECCU, Spain., Gutiérrez A; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital General Universitario Dr Balmis de Alicante; ISABIAL, Alicante, Spain., Barreiro-de Acosta M; Gastroenterology Department, Hospital Clínico Universitario de Santiago de Compostela, FIDIS, Santiago de Compostela, Spain.
Source: Therapeutic advances in gastroenterology [Therap Adv Gastroenterol] 2025 May 12; Vol. 18, pp. 17562848251338647. Date of Electronic Publication: 2025 May 12 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Sage Publications Country of Publication: England NLM ID: 101478893 Publication Model: eCollection Cited Medium: Print ISSN: 1756-283X (Print) Linking ISSN: 1756283X NLM ISO Abbreviation: Therap Adv Gastroenterol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Natural history, immunological and genetic characteristics of preclinical inflammatory bowel disease (EARLY): study protocol for a prospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Rodríguez-Lago+I%22">Rodríguez-Lago I</searchLink>; Gastroenterology Department, Hospital Universitario de Galdakao, Biobizkaia Health Research Institute, Galdakao 48960, Spain.<br /><searchLink fieldCode="AU" term="%22Marigorta+UM%22">Marigorta UM</searchLink>; Integrative Genomics Laboratory, CIC bioGUNE, Derio, Spain.<br /><searchLink fieldCode="AU" term="%22Mateos+B%22">Mateos B</searchLink>; Integrative Genomics Laboratory, CIC bioGUNE, Derio, Spain.<br /><searchLink fieldCode="AU" term="%22Mañosa+M%22">Mañosa M</searchLink>; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Márquez-Mosquera+L%22">Márquez-Mosquera L</searchLink>; Servei de Aparell Digestiu, Hospital del Mar; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Menchén+L%22">Menchén L</searchLink>; Gastroenterology Department, Hospital General Universitario e Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.; Departamento de Medicina, Universidad Complutense, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Moranta+F%22">Rodríguez-Moranta F</searchLink>; Gastroenterology Department, Hospital Universitario Bellvitge, IDIBELL, Hospitalet Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso+I%22">Alonso I</searchLink>; Gastroenterology Department, Hospital Universitario de Canarias, La Laguna, Spain.<br /><searchLink fieldCode="AU" term="%22Aguas+M%22">Aguas M</searchLink>; Gastroenterology Department, Hospital Politécnico y Universitario de la Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso-Galán+H%22">Alonso-Galán H</searchLink>; Gastroenterology Department, Hospital Universitario Donostia, BioGiopuzkoa Health Research Institute, Donostia, Spain.<br /><searchLink fieldCode="AU" term="%22Borràs+P%22">Borràs P</searchLink>; Gastroenterology Department, Hospital Universitari Mútua Terrassa, Terrassa, Spain.<br /><searchLink fieldCode="AU" term="%22Castro+B%22">Castro B</searchLink>; Gastroenterology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Domènech+E%22">Domènech E</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.<br /><searchLink fieldCode="AU" term="%22Ferreiro-Iglesias+R%22">Ferreiro-Iglesias R</searchLink>; Gastroenterology Department, Hospital Clínico Universitario de Santiago de Compostela, FIDIS, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22de+Francisco+R%22">de Francisco R</searchLink>; Gastroenterology Department, Hospital Universitario Central de Asturias, Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22García-Alonso+FJ%22">García-Alonso FJ</searchLink>; Gastroenterology Department, Hospital Universitario Río Hortega, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22García+N%22">García N</searchLink>; Gastroenterology Department, Hospital Álvaro Cunqueiro, Vigo, Spain.<br /><searchLink fieldCode="AU" term="%22García-Bosch+O%22">García-Bosch O</searchLink>; Gastroenterology Department, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Spain.<br /><searchLink fieldCode="AU" term="%22Gargallo+C%22">Gargallo C</searchLink>; Gastroenterology Department, Hospital Universitario Lozano Blesa, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Gisbert+JP%22">Gisbert JP</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Iglesias+E%22">Iglesias E</searchLink>; Gastroenterology Department, Hospital Universitario Reina Sofía, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Mesonero+F%22">Mesonero F</searchLink>; Gastroenterology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ortiz+de+Zárate+J%22">Ortiz de Zárate J</searchLink>; Gastroenterology Department, Hospital Universitario de Basurto, Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22Ramos+L%22">Ramos L</searchLink>; Gastroenterology Department, Hospital Universitario de Canarias, La Laguna, Spain.<br /><searchLink fieldCode="AU" term="%22Sáinz+E%22">Sáinz E</searchLink>; Gastroenterology Department, Hospital Universitari de Manresa, Manresa, Spain.<br /><searchLink fieldCode="AU" term="%22Ladrón+P%22">Ladrón P</searchLink>; Gastroenterology Department, Hospital Universitario de Burgos, Burgos, Spain.<br /><searchLink fieldCode="AU" term="%22Suria+C%22">Suria C</searchLink>; Gastroenterology Department, Hospital Clínico Universitario de Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Ferrer+CS%22">Ferrer CS</searchLink>; Gastroenterology Department, Hospital Universitario la Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tejido+C%22">Tejido C</searchLink>; Gastroenterology Department, Complejo Hospitalario de Ourense, Ourense, Spain.<br /><searchLink fieldCode="AU" term="%22Varela+P%22">Varela P</searchLink>; Gastroenterology Department, Hospital Universitario de Cabueñes, Gijón, Spain.<br /><searchLink fieldCode="AU" term="%22Vicente+R%22">Vicente R</searchLink>; Gastroenterology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Zabana+Y%22">Zabana Y</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital Universitari Mútua Terrassa, Terrassa, Spain.<br /><searchLink fieldCode="AU" term="%22Castany+G%22">Castany G</searchLink>; GETECCU, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+E%22">Rodríguez E</searchLink>; GETECCU, Spain.<br /><searchLink fieldCode="AU" term="%22Gutiérrez+A%22">Gutiérrez A</searchLink>; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.; Gastroenterology Department, Hospital General Universitario Dr Balmis de Alicante; ISABIAL, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Barreiro-de+Acosta+M%22">Barreiro-de Acosta M</searchLink>; Gastroenterology Department, Hospital Clínico Universitario de Santiago de Compostela, FIDIS, Santiago de Compostela, Spain.
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