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The impact of progressive chronic kidney disease on hepatic drug metabolism.

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Title: The impact of progressive chronic kidney disease on hepatic drug metabolism.
Authors: Hartjes ED; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Lim YJ; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Velenosi TJ; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Al KF; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada., Macklaim JM; Department of Microbiology & Immunology, Western University, London, Ontario, Canada., Kucey AS; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Reid G; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada., Burton JP; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada., Gloor GB; Department of Biochemistry, University of Western Ontario, London, Ontario, Canada., Urquhart BL; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Division of Nephrology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. Electronic address: Brad.Urquhart@schulich.uwo.ca.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 Jun; Vol. 53 (6), pp. 100085. Date of Electronic Publication: 2025 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The impact of progressive chronic kidney disease on hepatic drug metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Hartjes+ED%22">Hartjes ED</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lim+YJ%22">Lim YJ</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Velenosi+TJ%22">Velenosi TJ</searchLink>; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Al+KF%22">Al KF</searchLink>; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Macklaim+JM%22">Macklaim JM</searchLink>; Department of Microbiology & Immunology, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Kucey+AS%22">Kucey AS</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Reid+G%22">Reid G</searchLink>; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burton+JP%22">Burton JP</searchLink>; Department of Microbiology & Immunology, Western University, London, Ontario, Canada; Canadian Centre for Human Microbiome and Probiotics, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Gloor+GB%22">Gloor GB</searchLink>; Department of Biochemistry, University of Western Ontario, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Urquhart+BL%22">Urquhart BL</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Division of Nephrology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. Electronic address: Brad.Urquhart@schulich.uwo.ca.
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              Text: 2025 Jun
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