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Attenuation of mitochondrial dysfunction in a ventricular fibrillation swine model of cardiac arrest treated with carbon monoxide.

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Title: Attenuation of mitochondrial dysfunction in a ventricular fibrillation swine model of cardiac arrest treated with carbon monoxide.
Authors: Ko TS; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Greenwood JC; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Morgan RW; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Abella BS; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Shofer FS; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Mason M; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Weintraub D; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Bungatavula D; Drexel University, Philadelphia, PA 19104, USA., Lewis A; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA., Ranieri NR; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA; School of Biomedical Engineering, Science and Health Systems at Drexel University, Philadelphia, PA 19104, USA., Yodh AG; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA., Baker WB; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Forti RM; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA., Kao SH; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Shin SS; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Kilbaugh TJ; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Jang DH; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: David.Jang@pennmedicine.upenn.edu.
Source: Resuscitation [Resuscitation] 2025 Aug; Vol. 213, pp. 110647. Date of Electronic Publication: 2025 May 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier/north-Holland Biomedical Press Country of Publication: Ireland NLM ID: 0332173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1570 (Electronic) Linking ISSN: 03009572 NLM ISO Abbreviation: Resuscitation Subsets: MEDLINE
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  Data: Attenuation of mitochondrial dysfunction in a ventricular fibrillation swine model of cardiac arrest treated with carbon monoxide.
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  Data: <searchLink fieldCode="AU" term="%22Ko+TS%22">Ko TS</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Greenwood+JC%22">Greenwood JC</searchLink>; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+RW%22">Morgan RW</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Abella+BS%22">Abella BS</searchLink>; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Shofer+FS%22">Shofer FS</searchLink>; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Mason+M%22">Mason M</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Weintraub+D%22">Weintraub D</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Bungatavula+D%22">Bungatavula D</searchLink>; Drexel University, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+A%22">Lewis A</searchLink>; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Ranieri+NR%22">Ranieri NR</searchLink>; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA; School of Biomedical Engineering, Science and Health Systems at Drexel University, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Yodh+AG%22">Yodh AG</searchLink>; Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Baker+WB%22">Baker WB</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Forti+RM%22">Forti RM</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Kao+SH%22">Kao SH</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Shin+SS%22">Shin SS</searchLink>; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Kilbaugh+TJ%22">Kilbaugh TJ</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Jang+DH%22">Jang DH</searchLink>; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: David.Jang@pennmedicine.upenn.edu.
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