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First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.

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Title: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.
Authors: Kahlmann V; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Janssen Bonás M; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands., Moor CC; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands., Grutters JC; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands.; Division of Heart and Lungs, University Medical Center, Utrecht, the Netherlands., Mostard RLM; Department of Respiratory Medicine, Zuyderland Medical Center, Heerlen, the Netherlands.; Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, the Netherlands., van Rijswijk HNAJ; Department of Pulmonary Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., van der Maten J; Department of Pulmonary Diseases, Medical Center Leeuwarden, Leeuwarden, the Netherlands., Marges ER; Department of Pulmonary Medicine, Leiden University Medical Center, Leiden, the Netherlands., Moonen LAA; Department of Pulmonary Medicine, Rijnstate Hospital, Arnhem, the Netherlands., Overbeek MJ; Department of Pulmonary Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Department of Pulmonary Medicine, Haaglanden Medical Center, the Hague, the Netherlands., Koopman B; Department of Pulmonary Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam., Loth DW; Department of Pulmonary Medicine, Amphia, Breda, the Netherlands., Nossent EJ; Center of Expertise for Interstitial Lung Disease and Sarcoidosis, Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam., Wagenaar M; Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, the Netherlands., Kramer H; Department of Pulmonary Medicine, Martini Hospital, Groningen, the Netherlands., Wielders PLML; Department of Pulmonary Medicine, Catharina Hospital, Eindhoven, the Netherlands., Bonta PI; Center of Expertise for Interstitial Lung Disease and Sarcoidosis, Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam., Walen S; Department of Pulmonary Medicine, Isala Hospital, Zwolle, the Netherlands., Bogaarts BAHA; Department of Pulmonary Diseases, VieCuri Medical Center, Venlo, the Netherlands., Kerstens R; Orion Statistical Consulting, Hilvarenbeek, the Netherlands., Overgaauw M; Sarcoidosis Patient Association, Alkmaar, the Netherlands., Veltkamp M; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands.; Division of Heart and Lungs, University Medical Center, Utrecht, the Netherlands., Wijsenbeek MS; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Corporate Authors: PREDMETH Collaborators
Source: The New England journal of medicine [N Engl J Med] 2025 Jul 17; Vol. 393 (3), pp. 231-242. Date of Electronic Publication: 2025 May 18.
Publication Type: Clinical Trial, Phase IV; Equivalence Trial; Journal Article; Multicenter Study
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
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  Data: First-Line Treatment of Pulmonary Sarcoidosis with Prednisone or Methotrexate.
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  Data: <searchLink fieldCode="AU" term="%22Kahlmann+V%22">Kahlmann V</searchLink>; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Janssen+Bonás+M%22">Janssen Bonás M</searchLink>; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Moor+CC%22">Moor CC</searchLink>; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Grutters+JC%22">Grutters JC</searchLink>; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands.; Division of Heart and Lungs, University Medical Center, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Mostard+RLM%22">Mostard RLM</searchLink>; Department of Respiratory Medicine, Zuyderland Medical Center, Heerlen, the Netherlands.; Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Rijswijk+HNAJ%22">van Rijswijk HNAJ</searchLink>; Department of Pulmonary Medicine, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Maten+J%22">van der Maten J</searchLink>; Department of Pulmonary Diseases, Medical Center Leeuwarden, Leeuwarden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Marges+ER%22">Marges ER</searchLink>; Department of Pulmonary Medicine, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Moonen+LAA%22">Moonen LAA</searchLink>; Department of Pulmonary Medicine, Rijnstate Hospital, Arnhem, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Overbeek+MJ%22">Overbeek MJ</searchLink>; Department of Pulmonary Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Department of Pulmonary Medicine, Haaglanden Medical Center, the Hague, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Koopman+B%22">Koopman B</searchLink>; Department of Pulmonary Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam.<br /><searchLink fieldCode="AU" term="%22Loth+DW%22">Loth DW</searchLink>; Department of Pulmonary Medicine, Amphia, Breda, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Nossent+EJ%22">Nossent EJ</searchLink>; Center of Expertise for Interstitial Lung Disease and Sarcoidosis, Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam.<br /><searchLink fieldCode="AU" term="%22Wagenaar+M%22">Wagenaar M</searchLink>; Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kramer+H%22">Kramer H</searchLink>; Department of Pulmonary Medicine, Martini Hospital, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wielders+PLML%22">Wielders PLML</searchLink>; Department of Pulmonary Medicine, Catharina Hospital, Eindhoven, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bonta+PI%22">Bonta PI</searchLink>; Center of Expertise for Interstitial Lung Disease and Sarcoidosis, Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam.<br /><searchLink fieldCode="AU" term="%22Walen+S%22">Walen S</searchLink>; Department of Pulmonary Medicine, Isala Hospital, Zwolle, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bogaarts+BAHA%22">Bogaarts BAHA</searchLink>; Department of Pulmonary Diseases, VieCuri Medical Center, Venlo, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kerstens+R%22">Kerstens R</searchLink>; Orion Statistical Consulting, Hilvarenbeek, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Overgaauw+M%22">Overgaauw M</searchLink>; Sarcoidosis Patient Association, Alkmaar, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Veltkamp+M%22">Veltkamp M</searchLink>; Interstitial Lung Disease Center of Excellence (member of the European Reference Network on Rare Respiratory Diseases), St. Antonius Hospital, Nieuwegein, the Netherlands.; Division of Heart and Lungs, University Medical Center, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wijsenbeek+MS%22">Wijsenbeek MS</searchLink>; Center of Excellence for Interstitial Lung Diseases and Sarcoidosis (member of the European Reference Network on Rare Respiratory Diseases), Department of Respiratory Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.
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