Glucose-Lowering Medications, Glycemia, and Cognitive Outcomes: The GRADE Randomized Clinical Trial.

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Title: Glucose-Lowering Medications, Glycemia, and Cognitive Outcomes: The GRADE Randomized Clinical Trial.
Authors: Luchsinger JA; Department of Medicine, Columbia University Irving Medical Center, New York, New York.; Department of Epidemiology, Columbia University Irving Medical Center, New York, New York., Rosin SP; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland., Kazemi EJ; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland., Younes N; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland., Suratt CE; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland., Fattaleh BN; Veterans Affairs Puget Sound Health Care System, Seattle Institute for Biomedical and Clinical Research, Seattle, Washington., Florez HJ; Department of Medicine, University of Miami, Miami, Florida.; Department of Public Health Sciences, Medical University of South Carolina, Charleston.; Geriatric Research Education and Clinical Center, Bruce W. Carter Department of Veterans Affairs Medical Center, Miami, Florida., Gonzalez JS; Ferkauf Graduate School of Psychology, Yeshiva University, New York, New York.; Department of Medicine (Endocrinology), Albert Einstein College of Medicine, New York, New York.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York., Hollander P; Department of Medicine, Baylor Scott and White Health, Dallas, Texas., Hox SH; Department of Veterans Affairs, Pacific Islands Health Care System, Honolulu, Hawaii., Kuo S; Department of Internal Medicine, University of Michigan, Ann Arbor., Lee MS; Division of Endocrinology, Department of Medicine, State University of New York Down-State Medical Center, NYC Health and Hospitals/Kings County, New York., Martens T; International Diabetes Center, HealthPartners Institute, Minneapolis, Minnesota., Pop-Busui R; Department of Internal Medicine, University of Michigan, Ann Arbor., Seaquist ER; Department of Medicine, University of Minnesota, Minneapolis., Waltje AH; Department of Internal Medicine, University of Michigan, Ann Arbor., Barzilay JI; Division of Endocrinology, Kaiser Permanente of Georgia, Atlanta.; Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia.
Corporate Authors: GRADE Research Group
Source: JAMA internal medicine [JAMA Intern Med] 2025 Jul 01; Vol. 185 (7), pp. 778-787.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589534 Publication Model: Print Cited Medium: Internet ISSN: 2168-6114 (Electronic) Linking ISSN: 21686106 NLM ISO Abbreviation: JAMA Intern Med Subsets: MEDLINE
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  Data: Glucose-Lowering Medications, Glycemia, and Cognitive Outcomes: The GRADE Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Luchsinger+JA%22">Luchsinger JA</searchLink>; Department of Medicine, Columbia University Irving Medical Center, New York, New York.; Department of Epidemiology, Columbia University Irving Medical Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Rosin+SP%22">Rosin SP</searchLink>; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Kazemi+EJ%22">Kazemi EJ</searchLink>; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Younes+N%22">Younes N</searchLink>; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Suratt+CE%22">Suratt CE</searchLink>; Biostatistics Center, Department of Biostatistics and Bioinformatics, Milken Institute School of Public Health, George Washington University, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Fattaleh+BN%22">Fattaleh BN</searchLink>; Veterans Affairs Puget Sound Health Care System, Seattle Institute for Biomedical and Clinical Research, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Florez+HJ%22">Florez HJ</searchLink>; Department of Medicine, University of Miami, Miami, Florida.; Department of Public Health Sciences, Medical University of South Carolina, Charleston.; Geriatric Research Education and Clinical Center, Bruce W. Carter Department of Veterans Affairs Medical Center, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Gonzalez+JS%22">Gonzalez JS</searchLink>; Ferkauf Graduate School of Psychology, Yeshiva University, New York, New York.; Department of Medicine (Endocrinology), Albert Einstein College of Medicine, New York, New York.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hollander+P%22">Hollander P</searchLink>; Department of Medicine, Baylor Scott and White Health, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Hox+SH%22">Hox SH</searchLink>; Department of Veterans Affairs, Pacific Islands Health Care System, Honolulu, Hawaii.<br /><searchLink fieldCode="AU" term="%22Kuo+S%22">Kuo S</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Lee+MS%22">Lee MS</searchLink>; Division of Endocrinology, Department of Medicine, State University of New York Down-State Medical Center, NYC Health and Hospitals/Kings County, New York.<br /><searchLink fieldCode="AU" term="%22Martens+T%22">Martens T</searchLink>; International Diabetes Center, HealthPartners Institute, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Pop-Busui+R%22">Pop-Busui R</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Seaquist+ER%22">Seaquist ER</searchLink>; Department of Medicine, University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Waltje+AH%22">Waltje AH</searchLink>; Department of Internal Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Barzilay+JI%22">Barzilay JI</searchLink>; Division of Endocrinology, Kaiser Permanente of Georgia, Atlanta.; Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia.
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