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Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study.

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Title: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study.
Authors: Tesi B; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden., Robelius A; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden., Baskin B; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden., Lazarevic V; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden., Deneberg S; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden., Höglund M; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden., Fogelstrand L; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Gothenburg, Sweden., Ungerstedt J; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Linköping University Hospital, Linköping, Sweden., Pandzic T; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Tobiasson M; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden., Garelius HG; Department of Specialist Medicine, Section of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden., Kuchinskaya E; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Genetics, Linköping University, Linköping, Sweden.; Department of Clinical Experimental Medicine, Linköping University, Linköping, Sweden., Persson F; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden., Ågerstam H; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Lund, Sweden., Hallböök H; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden., Fioretos T; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Lund, Sweden.; Clinical Genomics Lund, Science for Life Laboratory, Lund University, Lund, Sweden., Nordin J; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Norberg A; Department of Medical Biosciences, Medical and Clinical Genetics, Umeå University, Umeå, Sweden., Thuresson AC; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden., Lehmann S; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden., Ladenvall C; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Barbany G; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Vennström L; Department of Specialist Medicine, Section of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden.; Institute of Medicine, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden., Ejerblad E; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden., Cavelier L; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Cammenga J; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.; Division of Molecular Medicine and Gene Therapy, Lund University, Lund, Sweden., Jädersten M; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden., Hellström-Lindberg E; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden., Baliakas P; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Jul 15; Vol. 31 (14), pp. 3062-3071.
Publication Type: Journal Article; Multicenter Study; Validation Study
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Tesi+B%22">Tesi B</searchLink>; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Robelius+A%22">Robelius A</searchLink>; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Baskin+B%22">Baskin B</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lazarevic+V%22">Lazarevic V</searchLink>; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Deneberg+S%22">Deneberg S</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Höglund+M%22">Höglund M</searchLink>; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Fogelstrand+L%22">Fogelstrand L</searchLink>; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ungerstedt+J%22">Ungerstedt J</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Linköping University Hospital, Linköping, Sweden.<br /><searchLink fieldCode="AU" term="%22Pandzic+T%22">Pandzic T</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Tobiasson+M%22">Tobiasson M</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Garelius+HG%22">Garelius HG</searchLink>; Department of Specialist Medicine, Section of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Kuchinskaya+E%22">Kuchinskaya E</searchLink>; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Genetics, Linköping University, Linköping, Sweden.; Department of Clinical Experimental Medicine, Linköping University, Linköping, Sweden.<br /><searchLink fieldCode="AU" term="%22Persson+F%22">Persson F</searchLink>; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ågerstam+H%22">Ågerstam H</searchLink>; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Hallböök+H%22">Hallböök H</searchLink>; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Fioretos+T%22">Fioretos T</searchLink>; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Lund, Sweden.; Clinical Genomics Lund, Science for Life Laboratory, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Nordin+J%22">Nordin J</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Norberg+A%22">Norberg A</searchLink>; Department of Medical Biosciences, Medical and Clinical Genetics, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Thuresson+AC%22">Thuresson AC</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lehmann+S%22">Lehmann S</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Ladenvall+C%22">Ladenvall C</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Barbany+G%22">Barbany G</searchLink>; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Vennström+L%22">Vennström L</searchLink>; Department of Specialist Medicine, Section of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden.; Institute of Medicine, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ejerblad+E%22">Ejerblad E</searchLink>; Department of Medical Sciences, Section of Hematology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Cavelier+L%22">Cavelier L</searchLink>; Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Cammenga+J%22">Cammenga J</searchLink>; Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.; Division of Molecular Medicine and Gene Therapy, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jädersten+M%22">Jädersten M</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hellström-Lindberg+E%22">Hellström-Lindberg E</searchLink>; Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Baliakas+P%22">Baliakas P</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden.; Clinical Genomics Uppsala, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Jul 15; Vol. 31 (14), pp. 3062-3071.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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