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Mineralocorticoid Receptor Antagonists and Aldosterone Synthase Inhibitors: Agent Comparison With Implications for Clinical Practice and Trial Design.

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Title: Mineralocorticoid Receptor Antagonists and Aldosterone Synthase Inhibitors: Agent Comparison With Implications for Clinical Practice and Trial Design.
Authors: Ferreira JP; UnIC@RISE, Cardiovascular Research and Development Center, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal; Heart Failure Clinic, Internal Medicine Department, Centro Hospitalar de Vila Nova de Gaia, Espinho, Portugal; Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, and INSERM U1116, CHRU, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France. Electronic address: jpferreira@med.up.pt., Marques P; UnIC@RISE, Cardiovascular Research and Development Center, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal; Internal Medicine Department, Centro Hospitalar Universitário de São João, Porto, Portugal., Leite AR; Endocrinology Department, Centro Hospitalar Universitário de São João, Porto, Portugal., Neves JS; UnIC@RISE, Cardiovascular Research and Development Center, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal; Endocrinology Department, Centro Hospitalar Universitário de São João, Porto, Portugal., Zannad F; Université de Lorraine, INSERM, Centre d'Investigations Cliniques Plurithématique 1433, and INSERM U1116, CHRU, F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France., Pitt B; Department of Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Source: Journal of cardiac failure [J Card Fail] 2026 Mar; Vol. 32 (3), pp. 633-646. Date of Electronic Publication: 2025 May 17.
Publication Type: Journal Article; Comparative Study; Review
Journal Info: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 9442138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8414 (Electronic) Linking ISSN: 10719164 NLM ISO Abbreviation: J Card Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-8414
DOI:10.1016/j.cardfail.2025.05.002