ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1.
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| Title: | ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. |
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| Authors: | Rincon-Torroella J; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States., Dal Molin M; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, United States., Mog B; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, United States., Han G; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States., Watson E; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States., Wyhs N; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States., Ishiyama S; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States., Ahmedna T; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States., Minn I; Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, United States., Azad N; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States., Bettegowda C; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Papadopoulos N; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Kinzler KW; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Zhou S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Vogelstein B; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States., Gabrielson K; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States., Sur S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States. |
| Source: | ELife [Elife] 2025 May 20; Vol. 13. Date of Electronic Publication: 2025 May 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40391649 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Rincon-Torroella+J%22">Rincon-Torroella J</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Dal+Molin+M%22">Dal Molin M</searchLink>; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Mog+B%22">Mog B</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Han+G%22">Han G</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Watson+E%22">Watson E</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Wyhs+N%22">Wyhs N</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Ishiyama+S%22">Ishiyama S</searchLink>; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Ahmedna+T%22">Ahmedna T</searchLink>; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Minn+I%22">Minn I</searchLink>; Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Azad+N%22">Azad N</searchLink>; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Bettegowda+C%22">Bettegowda C</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+N%22">Papadopoulos N</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Kinzler+KW%22">Kinzler KW</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Vogelstein+B%22">Vogelstein B</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Chevy Chase, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Gabrielson+K%22">Gabrielson K</searchLink>; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, United States.<br /><searchLink fieldCode="AU" term="%22Sur+S%22">Sur S</searchLink>; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, United States.; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, United States.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2025 May 20; Vol. 13. <i>Date of Electronic Publication: </i>2025 May 20. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40391649 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7554/eLife.94488 Languages: – Code: eng Text: English Titles: – TitleFull: ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Rincon-Torroella J – PersonEntity: Name: NameFull: Dal Molin M – PersonEntity: Name: NameFull: Mog B – PersonEntity: Name: NameFull: Han G – PersonEntity: Name: NameFull: Watson E – PersonEntity: Name: NameFull: Wyhs N – PersonEntity: Name: NameFull: Ishiyama S – PersonEntity: Name: NameFull: Ahmedna T – PersonEntity: Name: NameFull: Minn I – PersonEntity: Name: NameFull: Azad N – PersonEntity: Name: NameFull: Bettegowda C – PersonEntity: Name: NameFull: Papadopoulos N – PersonEntity: Name: NameFull: Kinzler KW – PersonEntity: Name: NameFull: Zhou S – PersonEntity: Name: NameFull: Vogelstein B – PersonEntity: Name: NameFull: Gabrielson K – PersonEntity: Name: NameFull: Sur S IsPartOfRelationships: – BibEntity: Dates: – D: 20 M: 05 Text: 2025 May 20 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2050-084X Numbering: – Type: volume Value: 13 Titles: – TitleFull: ELife Type: main |
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