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Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits.

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Title: Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits.
Authors: Currin KW; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Perrin HJ; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Pandey GK; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Alkhawaja AA; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Vadlamudi S; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Musser AE; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Etheridge AS; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.; Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Rosen JD; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Varshney A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA., Chaudhry AS; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Gallins PJ; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA., Wright FA; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695, USA., Zhou YH; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA., Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Schuetz EG; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Innocenti F; Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA; mohlke@med.unc.edu.
Source: Genome research [Genome Res] 2025 Jul 01; Vol. 35 (7), pp. 1485-1502. Date of Electronic Publication: 2025 Jul 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9518021 Publication Model: Electronic Cited Medium: Internet ISSN: 1549-5469 (Electronic) Linking ISSN: 10889051 NLM ISO Abbreviation: Genome Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits.
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  Data: <searchLink fieldCode="AU" term="%22Currin+KW%22">Currin KW</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Perrin+HJ%22">Perrin HJ</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+GK%22">Pandey GK</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Alkhawaja+AA%22">Alkhawaja AA</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Vadlamudi+S%22">Vadlamudi S</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Musser+AE%22">Musser AE</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Etheridge+AS%22">Etheridge AS</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.; Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Broadaway+KA%22">Broadaway KA</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Rosen+JD%22">Rosen JD</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Varshney+A%22">Varshney A</searchLink>; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhry+AS%22">Chaudhry AS</searchLink>; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.<br /><searchLink fieldCode="AU" term="%22Gallins+PJ%22">Gallins PJ</searchLink>; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA.<br /><searchLink fieldCode="AU" term="%22Wright+FA%22">Wright FA</searchLink>; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+YH%22">Zhou YH</searchLink>; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695, USA.; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA.<br /><searchLink fieldCode="AU" term="%22Parker+SCJ%22">Parker SCJ</searchLink>; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.<br /><searchLink fieldCode="AU" term="%22Raffield+LM%22">Raffield LM</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Schuetz+EG%22">Schuetz EG</searchLink>; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.<br /><searchLink fieldCode="AU" term="%22Innocenti+F%22">Innocenti F</searchLink>; Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.<br /><searchLink fieldCode="AU" term="%22Mohlke+KL%22">Mohlke KL</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA; mohlke@med.unc.edu.
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  Data: <searchLink fieldCode="JN" term="%229518021%22">Genome research</searchLink> [Genome Res] 2025 Jul 01; Vol. 35 (7), pp. 1485-1502. <i>Date of Electronic Publication: </i>2025 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cold+Spring+Harbor+Laboratory+Press%22">Cold Spring Harbor Laboratory Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9518021 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1549-5469 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210889051%22">10889051 </searchLink><i>NLM ISO Abbreviation: </i>Genome Res <i>Subsets: </i>MEDLINE
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