Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.

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Title: Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.
Authors: Wasehuus V; Steno Diabetes Center Copenhagen, Herlev, Denmark., Smeijer JD; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Ambery P; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Greasley PJ; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wijkmark E; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wheeler DC; Centre for Kidney and Bladder Health, University College London, London, UK., Rossing P; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; George Institute for Global Health, Barangaroo, New South Wales, Australia.
Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2025 Aug; Vol. 27 (8), pp. 4311-4319. Date of Electronic Publication: 2025 May 21.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Comparative Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.
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  Data: <searchLink fieldCode="AU" term="%22Wasehuus+V%22">Wasehuus V</searchLink>; Steno Diabetes Center Copenhagen, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Smeijer+JD%22">Smeijer JD</searchLink>; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ambery+P%22">Ambery P</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Greasley+PJ%22">Greasley PJ</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Wijkmark+E%22">Wijkmark E</searchLink>; BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Wheeler+DC%22">Wheeler DC</searchLink>; Centre for Kidney and Bladder Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rossing+P%22">Rossing P</searchLink>; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Heerspink+HJL%22">Heerspink HJL</searchLink>; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; George Institute for Global Health, Barangaroo, New South Wales, Australia.
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  Data: <searchLink fieldCode="JN" term="%22100883645%22">Diabetes, obesity & metabolism</searchLink> [Diabetes Obes Metab] 2025 Aug; Vol. 27 (8), pp. 4311-4319. <i>Date of Electronic Publication: </i>2025 May 21.
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  Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Comparative Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100883645 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1463-1326 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214628902%22">14628902 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Obes Metab <i>Subsets: </i>MEDLINE
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        Value: 10.1111/dom.16468
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      – Code: eng
        Text: English
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        StartPage: 4311
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      – TitleFull: Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non-diabetic chronic kidney disease.
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            – D: 01
              M: 08
              Text: 2025 Aug
              Type: published
              Y: 2025
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              Value: 1463-1326
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              Value: 27
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              Value: 8
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            – TitleFull: Diabetes, obesity & metabolism
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