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Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.

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Title: Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.
Authors: Faust Akl C; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Andersen BM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Veterans Affairs Medical Center, Harvard Medical School, Boston, MA, USA., Li Z; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Giovannoni F; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Diebold M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany., Sanmarco LM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kilian M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Fehrenbacher L; Institute of Neuropathology, University of Freiburg, Freiburg, Germany., Pernin F; Neuroimmunology Unit, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada., Rone JM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lee HG; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Piester G; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kenison JE; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lee JH; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Illouz T; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Polonio CM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Srun L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Martinez J; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Chung EN; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Schüle A; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Plasencia A; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Li L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Ferrara K; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lewandrowski M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Strathdee CA; Oncorus, Andover, MA, USA., Lerner L; Oncorus, Andover, MA, USA., Quéva C; Oncorus, Andover, MA, USA., Clark IC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Deneen B; Center for Cancer Neuroscience, Baylor College of Medicine, Houston, TX, USA., Lieberman J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Sherr DH; Department of Pathology, Boston University School of Medicine, Boston, MA, USA.; Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA., Antel JP; Neuroimmunology Unit, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada., Wheeler MA; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Gene Lay Institute of Immunology and Inflammation, Harvard Medical School, Boston, MA, USA., Ligon KL; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Chiocca EA; Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA., Prinz M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany., Reardon DA; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Quintana FJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. fquintana@rics.bwh.harvard.edu.; The Gene Lay Institute of Immunology and Inflammation, Harvard Medical School, Boston, MA, USA. fquintana@rics.bwh.harvard.edu.; The Broad Institute of Harvard and MIT, Cambridge, MA, USA. fquintana@rics.bwh.harvard.edu.
Source: Nature [Nature] 2025 Jul; Vol. 643 (8070), pp. 219-229. Date of Electronic Publication: 2025 May 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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