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Detection of Cancers Three Years prior to Diagnosis Using Plasma Cell-Free DNA.

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Title: Detection of Cancers Three Years prior to Diagnosis Using Plasma Cell-Free DNA.
Authors: Wang Y; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Joshu CE; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Curtis SD; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Douville C; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Division of Quantitative Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland., Burk VA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Ru M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Popoli M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Ptak J; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland., Dobbyn L; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Silliman N; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.; Department of Medicine, NYU Grossman School of Medicine, New York, New York.; Department of Population Health, NYU Grossman School of Medicine, New York, New York., Boerwinkle E; School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas., Prizment A; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota., Bettegowda C; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland., Kinzler KW; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Papadopoulos N; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland., Platz EA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Vogelstein B; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland.
Source: Cancer discovery [Cancer Discov] 2025 Sep 04; Vol. 15 (9), pp. 1794-1802.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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  Data: Detection of Cancers Three Years prior to Diagnosis Using Plasma Cell-Free DNA.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Joshu+CE%22">Joshu CE</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Curtis+SD%22">Curtis SD</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Douville+C%22">Douville C</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Division of Quantitative Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Burk+VA%22">Burk VA</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Ru+M%22">Ru M</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Popoli+M%22">Popoli M</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Ptak+J%22">Ptak J</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Dobbyn+L%22">Dobbyn L</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Silliman+N%22">Silliman N</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Coresh+J%22">Coresh J</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.; Department of Medicine, NYU Grossman School of Medicine, New York, New York.; Department of Population Health, NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Boerwinkle+E%22">Boerwinkle E</searchLink>; School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Prizment+A%22">Prizment A</searchLink>; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Bettegowda+C%22">Bettegowda C</searchLink>; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Kinzler+KW%22">Kinzler KW</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+N%22">Papadopoulos N</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Platz+EA%22">Platz EA</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Vogelstein+B%22">Vogelstein B</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Ludwig Center for Cancer Genetics and Therapeutics, Baltimore, Maryland.; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; The Howard Hughes Medical Institute, Baltimore, Maryland.
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