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A Novel Liquid Chromatography-Tandem Mass Spectrometry Method for Monitoring Plasma l -Asparaginase Activity in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Pegaspargase Treatment.

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Title: A Novel Liquid Chromatography-Tandem Mass Spectrometry Method for Monitoring Plasma l -Asparaginase Activity in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Pegaspargase Treatment.
Authors: Yu H; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Hu Q; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Liu L; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Xiang D; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Yang G; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Wang Y; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Wang Z; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Liu D; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and., Liu A; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Gong X; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.
Source: Therapeutic drug monitoring [Ther Drug Monit] 2025 Dec 01; Vol. 47 (6), pp. 755-763. Date of Electronic Publication: 2025 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3694 (Electronic) Linking ISSN: 01634356 NLM ISO Abbreviation: Ther Drug Monit Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Hu+Q%22">Hu Q</searchLink>; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Xiang+D%22">Xiang D</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.<br /><searchLink fieldCode="AU" term="%22Liu+A%22">Liu A</searchLink>; Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Gong+X%22">Gong X</searchLink>; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ; and.
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  Data: <searchLink fieldCode="JN" term="%227909660%22">Therapeutic drug monitoring</searchLink> [Ther Drug Monit] 2025 Dec 01; Vol. 47 (6), pp. 755-763. <i>Date of Electronic Publication: </i>2025 May 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7909660 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1536-3694 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201634356%22">01634356 </searchLink><i>NLM ISO Abbreviation: </i>Ther Drug Monit <i>Subsets: </i>MEDLINE
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              Text: 2025 Dec 01
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