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Timely germline BRCA testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study.

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Title: Timely germline BRCA testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study.
Authors: Kostov AM; Department of Surgical Pathology, Zealand University Hospital, Sygehusvej 9-11, 4000, Roskilde, Denmark., Jensen MB; Danish Breast Cancer Cooperative Group, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Ejlertsen B; Danish Breast Cancer Cooperative Group, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Clinical Genome Center, University of Southern Denmark and Region of Southern Denmark, Odense, Denmark., Rossing M; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Pedersen IS; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark.; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark., Petersen AH; Department of Clinical Genetics, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark., Christensen LL; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Wadt KAW; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Berrocal-Almanza LC; Oncology Outcomes Research, AstraZeneca, Cambridge, UK., Miranda M; Oncology Outcomes Research, AstraZeneca, Cambridge, UK., Lænkholm AV; Department of Surgical Pathology, Zealand University Hospital, Sygehusvej 9-11, 4000, Roskilde, Denmark. anlae@regionsjaelland.dk.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. anlae@regionsjaelland.dk.
Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2025 Jul; Vol. 212 (2), pp. 309-323. Date of Electronic Publication: 2025 May 23.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Timely germline BRCA testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study.
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  Data: <searchLink fieldCode="AU" term="%22Kostov+AM%22">Kostov AM</searchLink>; Department of Surgical Pathology, Zealand University Hospital, Sygehusvej 9-11, 4000, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+MB%22">Jensen MB</searchLink>; Danish Breast Cancer Cooperative Group, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ejlertsen+B%22">Ejlertsen B</searchLink>; Danish Breast Cancer Cooperative Group, Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Thomassen+M%22">Thomassen M</searchLink>; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Clinical Genome Center, University of Southern Denmark and Region of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Rossing+M%22">Rossing M</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+IS%22">Pedersen IS</searchLink>; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark.; Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Petersen+AH%22">Petersen AH</searchLink>; Department of Clinical Genetics, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Christensen+LL%22">Christensen LL</searchLink>; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Wadt+KAW%22">Wadt KAW</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Berrocal-Almanza+LC%22">Berrocal-Almanza LC</searchLink>; Oncology Outcomes Research, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Miranda+M%22">Miranda M</searchLink>; Oncology Outcomes Research, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lænkholm+AV%22">Lænkholm AV</searchLink>; Department of Surgical Pathology, Zealand University Hospital, Sygehusvej 9-11, 4000, Roskilde, Denmark. anlae@regionsjaelland.dk.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. anlae@regionsjaelland.dk.
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  Data: <searchLink fieldCode="JN" term="%228111104%22">Breast cancer research and treatment</searchLink> [Breast Cancer Res Treat] 2025 Jul; Vol. 212 (2), pp. 309-323. <i>Date of Electronic Publication: </i>2025 May 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8111104 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7217 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676806%22">01676806 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res Treat <i>Subsets: </i>MEDLINE
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              Text: 2025 Jul
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