Effectiveness and safety of chronic diuretic use in older adults: an umbrella review of recently published systematic reviews and meta-analyses of randomized-controlled trials.

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Title: Effectiveness and safety of chronic diuretic use in older adults: an umbrella review of recently published systematic reviews and meta-analyses of randomized-controlled trials.
Authors: van Poelgeest E; Section of Geriatrics, Department of Internal Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. e.p.vanpoelgeest@amsterdamumc.nl.; Amsterdam Public Health Research Institute, Aging and Later Life, Amsterdam, The Netherlands. e.p.vanpoelgeest@amsterdamumc.nl., Prokopidis K; Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK., Erdogan T; Division of Geriatrics, Department of Internal Medicine, Istanbul University, Istanbul Medical School, Istanbul, Turkey., Kwak MJ; Division of Geriatric and Palliative Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Piotrowicz K; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland., Paoletti L; Pharmacy Department, IRCCS San Raffaele Hospital, Milan, Italy., Eidam A; Geriatric Center, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany., Koçak FÖK; Division of Geriatrics, Department of Internal Medicine, Health Sciences University Tepecik Training and Research Hospital, İzmir, Turkey., Ilhan B; Division of Geriatrics, Department of Internal Medicine, Liv Hospital Vadistanbul, Istanbul, Turkey., Beccacece A; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy., Soulis G; Hellenic Society for the Study and Research of Ageing, Athens, Greece., Özkök S; Division of Geriatrics, Department of Internal Medicine, Istanbul University, Istanbul Medical School, Istanbul, Turkey., Bahat G; Division of Geriatrics, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey., Topinková E; Department of Geriatrics and Internal Medicine, 1st Faculty of Medicine Charles University, Prague, Czech Republic.; General Faculty Hospital in Prague, Faculty of Health and Social Sciences, University of South Bohemia, Ceske Budejovice, Czech Republic., Daams J; Medical Library, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Handoko ML; Department of Cardiology, University Medical Center Utrecht/Transplantation Center UMC Utrecht, Utrecht, The Netherlands.; Amsterdam University Medical Center, Amsterdam, The Netherlands., Goyal P; Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Gąsowski J; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland., Cherubini A; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.; Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy., Veronese N; Saint Camillus International University of Health Sciences, Rome, Italy., Testa GD; Department of Geriatric and Intensive Care Medicine, Careggi Hospital, University of Florence, Florence, Italy., Thompson W; Department of Anesthesiology, Pharmacology, and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada., van der Velde N; Section of Geriatrics, Department of Internal Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Aging and Later Life, Amsterdam, The Netherlands.
Corporate Authors: European Geriatric Medicine Society Special Interest Groups of i. Pharmacology; ii. Cardiovascular Disease and iii. Systematic Review and Meta-analysis
Source: European geriatric medicine [Eur Geriatr Med] 2025 Aug; Vol. 16 (4), pp. 1353-1387. Date of Electronic Publication: 2025 May 25.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101533694 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1878-7649 (Print) Linking ISSN: 18787649 NLM ISO Abbreviation: Eur Geriatr Med Subsets: MEDLINE
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  Data: Effectiveness and safety of chronic diuretic use in older adults: an umbrella review of recently published systematic reviews and meta-analyses of randomized-controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22van+Poelgeest+E%22">van Poelgeest E</searchLink>; Section of Geriatrics, Department of Internal Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. e.p.vanpoelgeest@amsterdamumc.nl.; Amsterdam Public Health Research Institute, Aging and Later Life, Amsterdam, The Netherlands. e.p.vanpoelgeest@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22Prokopidis+K%22">Prokopidis K</searchLink>; Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Erdogan+T%22">Erdogan T</searchLink>; Division of Geriatrics, Department of Internal Medicine, Istanbul University, Istanbul Medical School, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Kwak+MJ%22">Kwak MJ</searchLink>; Division of Geriatric and Palliative Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Piotrowicz+K%22">Piotrowicz K</searchLink>; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Paoletti+L%22">Paoletti L</searchLink>; Pharmacy Department, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Eidam+A%22">Eidam A</searchLink>; Geriatric Center, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Koçak+FÖK%22">Koçak FÖK</searchLink>; Division of Geriatrics, Department of Internal Medicine, Health Sciences University Tepecik Training and Research Hospital, İzmir, Turkey.<br /><searchLink fieldCode="AU" term="%22Ilhan+B%22">Ilhan B</searchLink>; Division of Geriatrics, Department of Internal Medicine, Liv Hospital Vadistanbul, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Beccacece+A%22">Beccacece A</searchLink>; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Soulis+G%22">Soulis G</searchLink>; 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Department of Cardiology, University Medical Center Utrecht/Transplantation Center UMC Utrecht, Utrecht, The Netherlands.; Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Goyal+P%22">Goyal P</searchLink>; Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gąsowski+J%22">Gąsowski J</searchLink>; Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Cherubini+A%22">Cherubini A</searchLink>; Geriatria, Accettazione geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.; Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Veronese+N%22">Veronese N</searchLink>; Saint Camillus International University of Health Sciences, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Testa+GD%22">Testa GD</searchLink>; Department of Geriatric and Intensive Care Medicine, Careggi Hospital, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Thompson+W%22">Thompson W</searchLink>; Department of Anesthesiology, Pharmacology, and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22van+der+Velde+N%22">van der Velde N</searchLink>; Section of Geriatrics, Department of Internal Medicine, Amsterdam University Medical Center, Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Aging and Later Life, Amsterdam, The Netherlands.
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