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A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.

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Bibliographic Details
Title: A Langendorff-heart discovery pipeline demonstrates cardiomyocyte targeting by extracellular vesicles functionalized with beta-blockers using click-chemistry.
Authors: Park KC; Department of Physiology, Anatomy & Genetics, Parks Road, Oxford OX1 3PT, UK., Jaafari AM; Department of Physiology, Anatomy & Genetics, Parks Road, Oxford OX1 3PT, UK., Smith CA; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Lobo AR; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Errichelli L; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Şimşek G; Department of Physiology, Anatomy & Genetics, Parks Road, Oxford OX1 3PT, UK; Department of Biophysics, Faculty of Medicine, Ankara University, Ankara, Türkiye., Gunadasa-Rohling M; Department of Physiology, Anatomy & Genetics, Parks Road, Oxford OX1 3PT, UK., Marchant A; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Levitin MO; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Castilla-Llorente V; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Vilela P; Evox Therapeutics, Medawar Centre, Robert Robinson Ave, Oxford OX4 4HG, UK., Swietach P; Department of Physiology, Anatomy & Genetics, Parks Road, Oxford OX1 3PT, UK. Electronic address: swietach@dpag.ox.ac.uk.
Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2025 Jul; Vol. 204, pp. 89-100. Date of Electronic Publication: 2025 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-8584
DOI:10.1016/j.yjmcc.2025.05.007