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Activated melanocytes and senescent collagen fibers predict laser-treated melasma outcomes: An optical biopsy-based prospective cohort study.

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Title: Activated melanocytes and senescent collagen fibers predict laser-treated melasma outcomes: An optical biopsy-based prospective cohort study.
Authors: Wang YJ; Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Cosmetic Applications and Management, MacKay Junior College of Medicine, Nursing, and Management, New Taipei City, Taiwan., Chang CC; Department of Cosmeceutics, China Medical University, Taichung, Taiwan; Institute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan, Taiwan; School of medicine, College of medicine, China medical university, China Medical University Hospital, Taichung, Taiwan; Aesthetic medical center, China Medical University Hospital, Taichung, Taiwan. Electronic address: changcc1975@gmail.com., Wu YH; Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan., Huang L; Apollo Medical Optics Ltd., Taipei, Taiwan., Chen IL; Apollo Medical Optics Ltd., Taipei, Taiwan., Shih YC; Apollo Medical Optics Ltd., Taipei, Taiwan., Cheng H; Apollo Medical Optics Ltd., Taipei, Taiwan., Shen JW; Department of Cosmeceutics, China Medical University, Taichung, Taiwan., Lu ME; Department of Cosmeceutics, China Medical University, Taichung, Taiwan., Chiang HM; Department of Cosmeceutics, China Medical University, Taichung, Taiwan., Lin BS; Institute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan, Taiwan.
Source: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2025 Aug; Vol. 54, pp. 104648. Date of Electronic Publication: 2025 May 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101226123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1597 (Electronic) Linking ISSN: 15721000 NLM ISO Abbreviation: Photodiagnosis Photodyn Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Activated melanocytes and senescent collagen fibers predict laser-treated melasma outcomes: An optical biopsy-based prospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Wang+YJ%22">Wang YJ</searchLink>; Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Cosmetic Applications and Management, MacKay Junior College of Medicine, Nursing, and Management, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CC%22">Chang CC</searchLink>; Department of Cosmeceutics, China Medical University, Taichung, Taiwan; Institute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan, Taiwan; School of medicine, College of medicine, China medical university, China Medical University Hospital, Taichung, Taiwan; Aesthetic medical center, China Medical University Hospital, Taichung, Taiwan. Electronic address: changcc1975@gmail.com.<br /><searchLink fieldCode="AU" term="%22Wu+YH%22">Wu YH</searchLink>; Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Apollo Medical Optics Ltd., Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IL%22">Chen IL</searchLink>; Apollo Medical Optics Ltd., Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+YC%22">Shih YC</searchLink>; Apollo Medical Optics Ltd., Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+H%22">Cheng H</searchLink>; Apollo Medical Optics Ltd., Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+JW%22">Shen JW</searchLink>; Department of Cosmeceutics, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lu+ME%22">Lu ME</searchLink>; Department of Cosmeceutics, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiang+HM%22">Chiang HM</searchLink>; Department of Cosmeceutics, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+BS%22">Lin BS</searchLink>; Institute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101226123%22">Photodiagnosis and photodynamic therapy</searchLink> [Photodiagnosis Photodyn Ther] 2025 Aug; Vol. 54, pp. 104648. <i>Date of Electronic Publication: </i>2025 May 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101226123 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-1597 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215721000%22">15721000 </searchLink><i>NLM ISO Abbreviation: </i>Photodiagnosis Photodyn Ther <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.pdpdt.2025.104648
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      – Code: eng
        Text: English
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        StartPage: 104648
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      – TitleFull: Activated melanocytes and senescent collagen fibers predict laser-treated melasma outcomes: An optical biopsy-based prospective cohort study.
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            – D: 01
              M: 08
              Text: 2025 Aug
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              Y: 2025
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