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Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response.

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Title: Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response.
Authors: Chen J; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA., Epstein MP; Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA 30322, USA., Schildkraut JM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA., Kar SP; Early Cancer Institute, University of Cambridge, Cambridge CB2 0AH, UK.; Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK.; Department of Oncology, University of Cambridge, Cambridge CB2 0AH, UK.
Source: Genes [Genes (Basel)] 2025 May 14; Vol. 16 (5). Date of Electronic Publication: 2025 May 14.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Epstein+MP%22">Epstein MP</searchLink>; Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Schildkraut+JM%22">Schildkraut JM</searchLink>; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Kar+SP%22">Kar SP</searchLink>; Early Cancer Institute, University of Cambridge, Cambridge CB2 0AH, UK.; Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge CB1 8RN, UK.; Department of Oncology, University of Cambridge, Cambridge CB2 0AH, UK.
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        Value: 10.3390/genes16050575
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        Text: English
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      – TitleFull: Mapping Inherited Genetic Variation with Opposite Effects on Autoimmune Disease and Four Cancer Types Identifies Candidate Drug Targets Associated with the Anti-Tumor Immune Response.
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            – D: 14
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              Text: 2025 May 14
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