HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy.
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| Title: | HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy. |
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| Authors: | Spadotto V; New Drug Incubator Department, Italfarmaco Group, Milan, Italy., Ripamonti C; New Drug Incubator Department, Italfarmaco Group, Milan, Italy., Ghiroldi A; New Drug Incubator Department, Italfarmaco Group, Milan, Italy., Galbiati E; Preclinical Drug Development Department, Italfarmaco Group, Milan, Italy., Pozzi P; Preclinical Drug Development Department, Italfarmaco Group, Milan, Italy., Noberini R; Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy., Bonaldi T; Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hematology-Oncology (DIPO), University of Milan, Milan, Italy., Steinkühler C; New Drug Incubator Department, Italfarmaco Group, Milan, Italy., Fossati G; New Drug Incubator Department, Italfarmaco Group, Milan, Italy. |
| Source: | Frontiers in immunology [Front Immunol] 2025 May 13; Vol. 16, pp. 1546939. Date of Electronic Publication: 2025 May 13 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40433358 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Spadotto+V%22">Spadotto V</searchLink>; New Drug Incubator Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ripamonti+C%22">Ripamonti C</searchLink>; New Drug Incubator Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ghiroldi+A%22">Ghiroldi A</searchLink>; New Drug Incubator Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Galbiati+E%22">Galbiati E</searchLink>; Preclinical Drug Development Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pozzi+P%22">Pozzi P</searchLink>; Preclinical Drug Development Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Noberini+R%22">Noberini R</searchLink>; Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonaldi+T%22">Bonaldi T</searchLink>; Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hematology-Oncology (DIPO), University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Steinkühler+C%22">Steinkühler C</searchLink>; New Drug Incubator Department, Italfarmaco Group, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fossati+G%22">Fossati G</searchLink>; New Drug Incubator Department, Italfarmaco Group, Milan, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 May 13; Vol. 16, pp. 1546939. <i>Date of Electronic Publication: </i>2025 May 13 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40433358 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3389/fimmu.2025.1546939 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1546939 Titles: – TitleFull: HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Spadotto V – PersonEntity: Name: NameFull: Ripamonti C – PersonEntity: Name: NameFull: Ghiroldi A – PersonEntity: Name: NameFull: Galbiati E – PersonEntity: Name: NameFull: Pozzi P – PersonEntity: Name: NameFull: Noberini R – PersonEntity: Name: NameFull: Bonaldi T – PersonEntity: Name: NameFull: Steinkühler C – PersonEntity: Name: NameFull: Fossati G IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 05 Text: 2025 May 13 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1664-3224 Numbering: – Type: volume Value: 16 Titles: – TitleFull: Frontiers in immunology Type: main |
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