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Exploring study dropout in drug trials for adults with PTSD: insights from a conventional and individual participant data meta-analysis.

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Title: Exploring study dropout in drug trials for adults with PTSD: insights from a conventional and individual participant data meta-analysis.
Authors: Wright SL; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; South Africa PTSD Research Programme of Excellence, Department of Psychiatry, Faculty of Medicine & Health Sciences, Stellenbosch University, Stellenbosch, South Africa., Kessler A; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department Public Mental Health, Central Institute of Mental Health, Mannheim, Germany., Sijbrandij M; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Karyotaki E; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Cuijpers P; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; International Institute for Psychotherapy, Babeș-Bolyai University, Cluj-Napoca, Romania., Bisson J; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Brady K; Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA., Dowd SM; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA., Dunlop BW; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Pollack MH; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA., Rothbaum BO; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Seedat S; South Africa PTSD Research Programme of Excellence, Department of Psychiatry, Faculty of Medicine & Health Sciences, Stellenbosch University, Stellenbosch, South Africa.; South African Medical Research Council Unit on the Genomics of Brain Disorders, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
Source: European journal of psychotraumatology [Eur J Psychotraumatol] 2025 Dec; Vol. 16 (1), pp. 2504839. Date of Electronic Publication: 2025 May 28.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101559025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2000-8066 (Electronic) Linking ISSN: 20008066 NLM ISO Abbreviation: Eur J Psychotraumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wright+SL%22">Wright SL</searchLink>; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; South Africa PTSD Research Programme of Excellence, Department of Psychiatry, Faculty of Medicine & Health Sciences, Stellenbosch University, Stellenbosch, South Africa.<br /><searchLink fieldCode="AU" term="%22Kessler+A%22">Kessler A</searchLink>; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department Public Mental Health, Central Institute of Mental Health, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Sijbrandij+M%22">Sijbrandij M</searchLink>; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Karyotaki+E%22">Karyotaki E</searchLink>; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cuijpers+P%22">Cuijpers P</searchLink>; Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; International Institute for Psychotherapy, Babeș-Bolyai University, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Bisson+J%22">Bisson J</searchLink>; Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Brady+K%22">Brady K</searchLink>; Psychiatry and Behavioral Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.<br /><searchLink fieldCode="AU" term="%22Dowd+SM%22">Dowd SM</searchLink>; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Dunlop+BW%22">Dunlop BW</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Pollack+MH%22">Pollack MH</searchLink>; Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Rothbaum+BO%22">Rothbaum BO</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Seedat+S%22">Seedat S</searchLink>; South Africa PTSD Research Programme of Excellence, Department of Psychiatry, Faculty of Medicine & Health Sciences, Stellenbosch University, Stellenbosch, South Africa.; South African Medical Research Council Unit on the Genomics of Brain Disorders, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
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