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Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation.

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Title: Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation.
Authors: Zhang J; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Hayat MA; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Si Y; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Guo T; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Ni Y; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Wang Q; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Hong Y; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Cao Y; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., He S; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Weng Z; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Li F; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China., Zuo H; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China., Sun X; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China., Chen B; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China., Hu J; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China. hu@ujs.edu.cn.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China. hu@ujs.edu.cn.; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China. hu@ujs.edu.cn.
Source: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2025 May 29; Vol. 74 (1), pp. 87. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9508160 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-908X (Electronic) Linking ISSN: 10233830 NLM ISO Abbreviation: Inflamm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Hayat+MA%22">Hayat MA</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Si+Y%22">Si Y</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Ni+Y%22">Ni Y</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Hong+Y%22">Hong Y</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22He+S%22">He S</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Weng+Z%22">Weng Z</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China.<br /><searchLink fieldCode="AU" term="%22Zuo+H%22">Zuo H</searchLink>; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Chen+B%22">Chen B</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China.<br /><searchLink fieldCode="AU" term="%22Hu+J%22">Hu J</searchLink>; Institute of Cerebrovascular Disease, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, 212002, China. hu@ujs.edu.cn.; Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, China. hu@ujs.edu.cn.; Zhenjiang Blood Center, Zhenjiang, 212013, Jiangsu, China. hu@ujs.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229508160%22">Inflammation research : official journal of the European Histamine Research Society ... [et al.]</searchLink> [Inflamm Res] 2025 May 29; Vol. 74 (1), pp. 87. <i>Date of Electronic Publication: </i>2025 May 29.
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        Value: 10.1007/s00011-025-02048-x
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