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Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes.

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Title: Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes.
Authors: Medford AJ; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Velimirovic M; Department of Hematology/Oncology, Cleveland Clinic, Cleveland, OH, USA., Gefen Y; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Niemierko A; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA., Gerratana L; Department of Medical Oncology, CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy., Davis AA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Clifton K; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Keenan J; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA., Podany E; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Hensing WL; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Reduzzi C; Weill Cornell Medicine, 420 E 70 th St, LH 204, New York, NY, 10021, USA., Dai CS; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Kiedrowski LA; Department of Medical Affairs, Guardant Health, Redwood City, CA, USA., Spring LM; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA., Ellisen LW; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA., Doebele RC; Rain Therapeutics, Newark, CA, USA., Cristofanilli M; Weill Cornell Medicine, 420 E 70 th St, LH 204, New York, NY, 10021, USA., Getz G; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Bardia A; David Geffen School of Medicine at UCLA & UCLA Health Jonsson Comprehensive Cancer Center, Los Angeles, CA, 90024, USA. ABardia@mednet.ucla.edu.
Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2025 Aug; Vol. 212 (3), pp. 437-447. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
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  Data: Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes.
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  Data: <searchLink fieldCode="AU" term="%22Medford+AJ%22">Medford AJ</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Velimirovic+M%22">Velimirovic M</searchLink>; Department of Hematology/Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Gefen+Y%22">Gefen Y</searchLink>; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Niemierko+A%22">Niemierko A</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gerratana+L%22">Gerratana L</searchLink>; Department of Medical Oncology, CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Davis+AA%22">Davis AA</searchLink>; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Clifton+K%22">Clifton K</searchLink>; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Keenan+J%22">Keenan J</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Podany+E%22">Podany E</searchLink>; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hensing+WL%22">Hensing WL</searchLink>; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Reduzzi+C%22">Reduzzi C</searchLink>; Weill Cornell Medicine, 420 E 70 th St, LH 204, New York, NY, 10021, USA.<br /><searchLink fieldCode="AU" term="%22Dai+CS%22">Dai CS</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kiedrowski+LA%22">Kiedrowski LA</searchLink>; Department of Medical Affairs, Guardant Health, Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Spring+LM%22">Spring LM</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ellisen+LW%22">Ellisen LW</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Doebele+RC%22">Doebele RC</searchLink>; Rain Therapeutics, Newark, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cristofanilli+M%22">Cristofanilli M</searchLink>; Weill Cornell Medicine, 420 E 70 th St, LH 204, New York, NY, 10021, USA.<br /><searchLink fieldCode="AU" term="%22Getz+G%22">Getz G</searchLink>; Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bardia+A%22">Bardia A</searchLink>; David Geffen School of Medicine at UCLA & UCLA Health Jonsson Comprehensive Cancer Center, Los Angeles, CA, 90024, USA. ABardia@mednet.ucla.edu.
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  Data: <searchLink fieldCode="JN" term="%228111104%22">Breast cancer research and treatment</searchLink> [Breast Cancer Res Treat] 2025 Aug; Vol. 212 (3), pp. 437-447. <i>Date of Electronic Publication: </i>2025 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%22">Kluwer Academic </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8111104 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-7217 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201676806%22">01676806 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res Treat <i>Subsets: </i>MEDLINE
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