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High resolution clonal architecture of hypomutated Wilms tumours.

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Title: High resolution clonal architecture of hypomutated Wilms tumours.
Authors: Lee-Six H; Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Treger TD; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK., Dave M; Wellcome Sanger Institute, Hinxton, UK.; Department of Biochemistry, The University of Cambridge, Cambridge, UK.; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK., Coorens TH; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Anderson ND; Wellcome Sanger Institute, Hinxton, UK., Tiersma Y; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., Derakhshan S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., de Haan S; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands., van den Heuvel-Eibrink MM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Wang Y; Wellcome Sanger Institute, Hinxton, UK., Wenger A; Wellcome Sanger Institute, Hinxton, UK., Al-Saadi R; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK., Lawford A; Great Ormond Street Hospital for Children, London, UK., Letunovska A; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK., Wegert J; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, Würzburg University & Comprehensive Cancer Center Mainfranken, Würzburg, Germany., Parks C; Wellcome Sanger Institute, Hinxton, UK., Morcrette G; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK., Gessler M; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, Würzburg University & Comprehensive Cancer Center Mainfranken, Würzburg, Germany., Vujanic G; Department of Pathology, Sidra Medicine, Doha, Qatar., Chowdhury T; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK., J O'Sullivan M; Department of Pathology, Children's Health Ireland at Crumlin, Dublin, Ireland.; Histopathology Department, The University of Dublin, Trinity College, Dublin, Ireland., de Krijger RR; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Stratton MR; Wellcome Sanger Institute, Hinxton, UK., Pritchard-Jones K; UCL Great Ormond Street Institute of Child Health, London, UK., Hutchinson JC; Great Ormond Street Hospital for Children, London, UK. Ciaran.hutchinson@gosh.nhs.uk., Drost J; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. j.drost@prinsesmaximacentrum.nl.; Oncode Institute, Utrecht, The Netherlands. j.drost@prinsesmaximacentrum.nl., Behjati S; Wellcome Sanger Institute, Hinxton, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, UK. sb31@sanger.ac.uk.
Source: Nature communications [Nat Commun] 2025 May 29; Vol. 16 (1), pp. 4647. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Lee-Six+H%22">Lee-Six H</searchLink>; Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Treger+TD%22">Treger TD</searchLink>; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Dave+M%22">Dave M</searchLink>; Wellcome Sanger Institute, Hinxton, UK.; Department of Biochemistry, The University of Cambridge, Cambridge, UK.; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Coorens+TH%22">Coorens TH</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+ND%22">Anderson ND</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Tiersma+Y%22">Tiersma Y</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Derakhshan+S%22">Derakhshan S</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Haan+S%22">de Haan S</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Heuvel-Eibrink+MM%22">van den Heuvel-Eibrink MM</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Wenger+A%22">Wenger A</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Al-Saadi+R%22">Al-Saadi R</searchLink>; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22Lawford+A%22">Lawford A</searchLink>; Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22Letunovska+A%22">Letunovska A</searchLink>; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22Wegert+J%22">Wegert J</searchLink>; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, Würzburg University & Comprehensive Cancer Center Mainfranken, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Parks+C%22">Parks C</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Morcrette+G%22">Morcrette G</searchLink>; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22Gessler+M%22">Gessler M</searchLink>; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, Würzburg University & Comprehensive Cancer Center Mainfranken, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vujanic+G%22">Vujanic G</searchLink>; Department of Pathology, Sidra Medicine, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Chowdhury+T%22">Chowdhury T</searchLink>; UCL Great Ormond Street Institute of Child Health, London, UK.; Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22J+O'Sullivan+M%22">J O'Sullivan M</searchLink>; Department of Pathology, Children's Health Ireland at Crumlin, Dublin, Ireland.; Histopathology Department, The University of Dublin, Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22de+Krijger+RR%22">de Krijger RR</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stratton+MR%22">Stratton MR</searchLink>; Wellcome Sanger Institute, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Pritchard-Jones+K%22">Pritchard-Jones K</searchLink>; UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Hutchinson+JC%22">Hutchinson JC</searchLink>; Great Ormond Street Hospital for Children, London, UK. Ciaran.hutchinson@gosh.nhs.uk.<br /><searchLink fieldCode="AU" term="%22Drost+J%22">Drost J</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. j.drost@prinsesmaximacentrum.nl.; Oncode Institute, Utrecht, The Netherlands. j.drost@prinsesmaximacentrum.nl.<br /><searchLink fieldCode="AU" term="%22Behjati+S%22">Behjati S</searchLink>; Wellcome Sanger Institute, Hinxton, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, UK. sb31@sanger.ac.uk.
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