Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex.
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| Title: | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex. |
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| Authors: | Chen M; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Nguyen TN; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Ren X; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Khuu G; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Cook ASI; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA., Zhao Y; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Physics Department, University of California, Berkeley, Berkeley, CA, USA., Yildiz A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA.; Physics Department, University of California, Berkeley, Berkeley, CA, USA., Lazarou M; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Hurley JH; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. jimhurley@berkeley.edu.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu. |
| Source: | Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Sep; Vol. 32 (9), pp. 1596-1605. Date of Electronic Publication: 2025 May 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40442316 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+TN%22">Nguyen TN</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ren+X%22">Ren X</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Khuu+G%22">Khuu G</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Cook+ASI%22">Cook ASI</searchLink>; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Physics Department, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yildiz+A%22">Yildiz A</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA.; Physics Department, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lazarou+M%22">Lazarou M</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hurley+JH%22">Hurley JH</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. jimhurley@berkeley.edu.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA. jimhurley@berkeley.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101186374%22">Nature structural & molecular biology</searchLink> [Nat Struct Mol Biol] 2025 Sep; Vol. 32 (9), pp. 1596-1605. <i>Date of Electronic Publication: </i>2025 May 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101186374 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-9985 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215459985%22">15459985 </searchLink><i>NLM ISO Abbreviation: </i>Nat Struct Mol Biol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40442316 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41594-025-01557-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1596 Titles: – TitleFull: Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chen M – PersonEntity: Name: NameFull: Nguyen TN – PersonEntity: Name: NameFull: Ren X – PersonEntity: Name: NameFull: Khuu G – PersonEntity: Name: NameFull: Cook ASI – PersonEntity: Name: NameFull: Zhao Y – PersonEntity: Name: NameFull: Yildiz A – PersonEntity: Name: NameFull: Lazarou M – PersonEntity: Name: NameFull: Hurley JH IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2025 Sep Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1545-9985 Numbering: – Type: volume Value: 32 – Type: issue Value: 9 Titles: – TitleFull: Nature structural & molecular biology Type: main |
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