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Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities.

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Title: Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities.
Authors: Morais GP; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., de Sousa Neto IV; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., Veras ASC; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Teixeira GR; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Paroschi LO; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., Pinto AP; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., Dos Santos JR; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., Alberici LC; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil., Cintra DEC; Laboratory of Nutritional Genomic, School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.; Lipids and Nutrigenomics Research Center (CELN), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil., Pauli JR; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.; Lipids and Nutrigenomics Research Center (CELN), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil., Morelli AP; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil., Ropelle ER; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil., da Silva ASR; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. adelinosanchez@usp.br.; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. adelinosanchez@usp.br.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Oct; Vol. 62 (10), pp. 12791-12810. Date of Electronic Publication: 2025 May 31.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
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  Data: Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities.
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  Data: <searchLink fieldCode="AU" term="%22Morais+GP%22">Morais GP</searchLink>; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Sousa+Neto+IV%22">de Sousa Neto IV</searchLink>; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Veras+ASC%22">Veras ASC</searchLink>; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Teixeira+GR%22">Teixeira GR</searchLink>; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Paroschi+LO%22">Paroschi LO</searchLink>; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Pinto+AP%22">Pinto AP</searchLink>; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+JR%22">Dos Santos JR</searchLink>; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Alberici+LC%22">Alberici LC</searchLink>; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Cintra+DEC%22">Cintra DEC</searchLink>; Laboratory of Nutritional Genomic, School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.; Lipids and Nutrigenomics Research Center (CELN), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Pauli+JR%22">Pauli JR</searchLink>; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.; Lipids and Nutrigenomics Research Center (CELN), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Morelli+AP%22">Morelli AP</searchLink>; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ropelle+ER%22">Ropelle ER</searchLink>; Laboratory of Molecular Biology of Exercise (LaBMEx), Faculty of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+ASR%22">da Silva ASR</searchLink>; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. adelinosanchez@usp.br.; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. adelinosanchez@usp.br.
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  Data: <searchLink fieldCode="JN" term="%228900963%22">Molecular neurobiology</searchLink> [Mol Neurobiol] 2025 Oct; Vol. 62 (10), pp. 12791-12810. <i>Date of Electronic Publication: </i>2025 May 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Humana+Press%22">Humana Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8900963 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-1182 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208937648%22">08937648 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurobiol <i>Subsets: </i>MEDLINE
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