Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma.
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| Title: | Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma. |
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| Authors: | Shi R; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Farnsworth DA; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Febres-Aldana CA; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chow JLM; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Sheena R; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Atwal T; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Gomez Marti JL; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li S; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Thomas KN; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Lee CM; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Awrey SJ; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., McDonald PC; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada., Somwar R; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dedhar S; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Ladanyi M; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Bennewith KL; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Lockwood WW; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada. wlockwood@bccrc.ca.; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. wlockwood@bccrc.ca. |
| Source: | Oncogene [Oncogene] 2025 Aug; Vol. 44 (32), pp. 2831-2849. Date of Electronic Publication: 2025 May 31. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40450112 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Shi+R%22">Shi R</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Farnsworth+DA%22">Farnsworth DA</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Febres-Aldana+CA%22">Febres-Aldana CA</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chow+JLM%22">Chow JLM</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Sheena+R%22">Sheena R</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Atwal+T%22">Atwal T</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Gomez+Marti+JL%22">Gomez Marti JL</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Thomas+KN%22">Thomas KN</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+CM%22">Lee CM</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Awrey+SJ%22">Awrey SJ</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22McDonald+PC%22">McDonald PC</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Somwar+R%22">Somwar R</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dedhar+S%22">Dedhar S</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Ladanyi+M%22">Ladanyi M</searchLink>; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bennewith+KL%22">Bennewith KL</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada.; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lockwood+WW%22">Lockwood WW</searchLink>; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC, Canada. wlockwood@bccrc.ca.; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. wlockwood@bccrc.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2025 Aug; Vol. 44 (32), pp. 2831-2849. <i>Date of Electronic Publication: </i>2025 May 31. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40450112 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41388-025-03461-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2831 Titles: – TitleFull: Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shi R – PersonEntity: Name: NameFull: Farnsworth DA – PersonEntity: Name: NameFull: Febres-Aldana CA – PersonEntity: Name: NameFull: Chow JLM – PersonEntity: Name: NameFull: Sheena R – PersonEntity: Name: NameFull: Atwal T – PersonEntity: Name: NameFull: Gomez Marti JL – PersonEntity: Name: NameFull: Li S – PersonEntity: Name: NameFull: Thomas KN – PersonEntity: Name: NameFull: Lee CM – PersonEntity: Name: NameFull: Awrey SJ – PersonEntity: Name: NameFull: McDonald PC – PersonEntity: Name: NameFull: Somwar R – PersonEntity: Name: NameFull: Dedhar S – PersonEntity: Name: NameFull: Ladanyi M – PersonEntity: Name: NameFull: Bennewith KL – PersonEntity: Name: NameFull: Lockwood WW IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2025 Aug Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1476-5594 Numbering: – Type: volume Value: 44 – Type: issue Value: 32 Titles: – TitleFull: Oncogene Type: main |
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