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Real-world data on the effect of long-term treatment with nusinersen over > 4 years in a cohort of Swiss patients with spinal muscular atrophy.

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Title: Real-world data on the effect of long-term treatment with nusinersen over > 4 years in a cohort of Swiss patients with spinal muscular atrophy.
Authors: Tscherter A; Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, Bern 3012, Switzerland. Electronic address: anne.tscherter@unibe.ch., Steiner L; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland., Broser PJ; Paediatric Neurology, Children's Hospital of Eastern Switzerland, Claudiusstrasse 6, 9000 St. Gallen, Switzerland; Medical Faculty, University of Basel, Klingelbergstrasse 61, Basel 4056, Switzerland., Enzmann C; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel (UKBB), University of Basel, Spitalstrasse 33, Basel 4031, Switzerland., Galiart E; Neuromuscular Center Zurich, Department of Pediatric Neurology, University Children's Hospital Zurich, University of Zurich, Lenggstrasse 30, Zürich 8008, Switzerland., Henzi BC; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel (UKBB), University of Basel, Spitalstrasse 33, Basel 4031, Switzerland., Jacquier D; Pediatric neurology and Neurorehabilitation Unit, Lausanne University Hospital, Av. Pierre Decker 5, Lausanne 1011, Switzerland., Mathis AM; Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, Bern 3012, Switzerland., Neuwirth C; Neuromuscular Diseases Unit/ALS Clinic, Cantonal Hospital St. Gallen, Rorschacher Str. 95/Haus 33, 9007 St. Gallen, Switzerland., Ramelli GP; Neuropediatrics Unit, Paediatric Institute of Southern Switzerland, EOC, Via Ospedale 12, Bellinzona 6500, Switzerland., Ripellino P; Department of Neurology, Neurocenter of Southern Switzerland EOC, Via Tesserete 46, Lugano 6900, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Via la Santa 1, Lugano 6900, Switzerland., Scheidegger O; Centre for Neuromuscular Diseases, Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Rosenbühlgasse 25, Bern 3010, Switzerland., Schreiner B; Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, Zürich 8091, Switzerland., Schwarz EI; Sleep Disorders Centre and Ventilation Unit, Department of Pulmonology, University Hospital Zurich and University of Zurich, Rämistrasse 100, Zürich 8091, Switzerland., Stettner GM; Neuromuscular Center Zurich, Department of Pediatric Neurology, University Children's Hospital Zurich, University of Zurich, Lenggstrasse 30, Zürich 8008, Switzerland., Klein A; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland.
Corporate Authors: Swiss-Reg-NMD Group
Source: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2025 Aug; Vol. 255, pp. 108983. Date of Electronic Publication: 2025 May 26.
Publication Type: Journal Article; Observational Study; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7502039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6968 (Electronic) Linking ISSN: 03038467 NLM ISO Abbreviation: Clin Neurol Neurosurg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world data on the effect of long-term treatment with nusinersen over > 4 years in a cohort of Swiss patients with spinal muscular atrophy.
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  Data: <searchLink fieldCode="AU" term="%22Tscherter+A%22">Tscherter A</searchLink>; Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, Bern 3012, Switzerland. Electronic address: anne.tscherter@unibe.ch.<br /><searchLink fieldCode="AU" term="%22Steiner+L%22">Steiner L</searchLink>; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland.<br /><searchLink fieldCode="AU" term="%22Broser+PJ%22">Broser PJ</searchLink>; Paediatric Neurology, Children's Hospital of Eastern Switzerland, Claudiusstrasse 6, 9000 St. Gallen, Switzerland; Medical Faculty, University of Basel, Klingelbergstrasse 61, Basel 4056, Switzerland.<br /><searchLink fieldCode="AU" term="%22Enzmann+C%22">Enzmann C</searchLink>; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel (UKBB), University of Basel, Spitalstrasse 33, Basel 4031, Switzerland.<br /><searchLink fieldCode="AU" term="%22Galiart+E%22">Galiart E</searchLink>; Neuromuscular Center Zurich, Department of Pediatric Neurology, University Children's Hospital Zurich, University of Zurich, Lenggstrasse 30, Zürich 8008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Henzi+BC%22">Henzi BC</searchLink>; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland; Division of Neuropediatrics and Developmental Medicine, University Children's Hospital Basel (UKBB), University of Basel, Spitalstrasse 33, Basel 4031, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jacquier+D%22">Jacquier D</searchLink>; Pediatric neurology and Neurorehabilitation Unit, Lausanne University Hospital, Av. Pierre Decker 5, Lausanne 1011, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mathis+AM%22">Mathis AM</searchLink>; Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, Bern 3012, Switzerland.<br /><searchLink fieldCode="AU" term="%22Neuwirth+C%22">Neuwirth C</searchLink>; Neuromuscular Diseases Unit/ALS Clinic, Cantonal Hospital St. Gallen, Rorschacher Str. 95/Haus 33, 9007 St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ramelli+GP%22">Ramelli GP</searchLink>; Neuropediatrics Unit, Paediatric Institute of Southern Switzerland, EOC, Via Ospedale 12, Bellinzona 6500, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ripellino+P%22">Ripellino P</searchLink>; Department of Neurology, Neurocenter of Southern Switzerland EOC, Via Tesserete 46, Lugano 6900, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Via la Santa 1, Lugano 6900, Switzerland.<br /><searchLink fieldCode="AU" term="%22Scheidegger+O%22">Scheidegger O</searchLink>; Centre for Neuromuscular Diseases, Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Rosenbühlgasse 25, Bern 3010, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schreiner+B%22">Schreiner B</searchLink>; Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, Zürich 8091, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schwarz+EI%22">Schwarz EI</searchLink>; Sleep Disorders Centre and Ventilation Unit, Department of Pulmonology, University Hospital Zurich and University of Zurich, Rämistrasse 100, Zürich 8091, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stettner+GM%22">Stettner GM</searchLink>; Neuromuscular Center Zurich, Department of Pediatric Neurology, University Children's Hospital Zurich, University of Zurich, Lenggstrasse 30, Zürich 8008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Klein+A%22">Klein A</searchLink>; Division of Neuropediatrics, Development and Rehabilitation, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern 3010, Switzerland.
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