View in EDS

Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.

Saved in:
Bibliographic Details
Title: Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.
Authors: Vigneron SF; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Ohno S; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States., Braz J; Department of Anatomy, University of California, San Francisco, California 94158, United States., Kim JY; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Kweon OS; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States., Webb C; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Billesbølle CB; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Srinivasan K; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Bhardwaj K; Department of Anatomy, University of California, San Francisco, California 94158, United States., Irwin JJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Manglik A; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States., Basbaum AI; Department of Anatomy, University of California, San Francisco, California 94158, United States., Ellman JA; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States., Shoichet BK; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.
Source: ACS central science [ACS Cent Sci] 2025 Apr 29; Vol. 11 (5), pp. 770-790. Date of Electronic Publication: 2025 Apr 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: eCollection Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40454334
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Vigneron+SF%22">Vigneron SF</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Ohno+S%22">Ohno S</searchLink>; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.<br /><searchLink fieldCode="AU" term="%22Braz+J%22">Braz J</searchLink>; Department of Anatomy, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Kim+JY%22">Kim JY</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Kweon+OS%22">Kweon OS</searchLink>; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.<br /><searchLink fieldCode="AU" term="%22Webb+C%22">Webb C</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Billesbølle+CB%22">Billesbølle CB</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Srinivasan+K%22">Srinivasan K</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Bhardwaj+K%22">Bhardwaj K</searchLink>; Department of Anatomy, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Irwin+JJ%22">Irwin JJ</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Manglik+A%22">Manglik A</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Basbaum+AI%22">Basbaum AI</searchLink>; Department of Anatomy, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Ellman+JA%22">Ellman JA</searchLink>; Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.<br /><searchLink fieldCode="AU" term="%22Shoichet+BK%22">Shoichet BK</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101660035%22">ACS central science</searchLink> [ACS Cent Sci] 2025 Apr 29; Vol. 11 (5), pp. 770-790. <i>Date of Electronic Publication: </i>2025 Apr 29 (<i>Print Publication: </i>2025).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ACS+Publications%22">ACS Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101660035 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2374-7943 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223747943%22">23747943 </searchLink><i>NLM ISO Abbreviation: </i>ACS Cent Sci <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40454334
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acscentsci.5c00052
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 770
    Titles:
      – TitleFull: Docking 14 Million Virtual Isoquinuclidines against the μ and κ Opioid Receptors Reveals Dual Antagonists-Inverse Agonists with Reduced Withdrawal Effects.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Vigneron SF
      – PersonEntity:
          Name:
            NameFull: Ohno S
      – PersonEntity:
          Name:
            NameFull: Braz J
      – PersonEntity:
          Name:
            NameFull: Kim JY
      – PersonEntity:
          Name:
            NameFull: Kweon OS
      – PersonEntity:
          Name:
            NameFull: Webb C
      – PersonEntity:
          Name:
            NameFull: Billesbølle CB
      – PersonEntity:
          Name:
            NameFull: Srinivasan K
      – PersonEntity:
          Name:
            NameFull: Bhardwaj K
      – PersonEntity:
          Name:
            NameFull: Irwin JJ
      – PersonEntity:
          Name:
            NameFull: Manglik A
      – PersonEntity:
          Name:
            NameFull: Basbaum AI
      – PersonEntity:
          Name:
            NameFull: Ellman JA
      – PersonEntity:
          Name:
            NameFull: Shoichet BK
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 29
              M: 04
              Text: 2025 Apr 29
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 2374-7943
          Numbering:
            – Type: volume
              Value: 11
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: ACS central science
              Type: main
ResultId 1