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Clinical Validation of a Circulating Tumor DNA-Based Blood Test to Screen for Colorectal Cancer.

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Title: Clinical Validation of a Circulating Tumor DNA-Based Blood Test to Screen for Colorectal Cancer.
Authors: Shaukat A; NYU Grossman School of Medicine, New York, New York.; University of Minnesota Twin Cities, Minneapolis., Burke CA; Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, Ohio., Chan AT; Massachusetts General Hospital, Boston, Massachusetts., Grady WM; Fred Hutchinson Cancer Center, Seattle, Washington.; University of Washington School of Medicine, Seattle., Gupta S; University of California, San Diego., Katona BW; University of Pennsylvania Perelman School of Medicine, Philadelphia., Ladabaum U; Stanford University School of Medicine, Stanford, California., Liang PS; NYU Grossman School of Medicine, New York, New York., Liu JJ; Morehouse School of Medicine, Atlanta, Georgia., Putcha G; Freenome Holdings Inc, Brisbane, California.; Now with Precision Medicine and Diagnostics, Los Altos Hills, California., Robertson DJ; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Schoen RE; Departments of Medicine and Epidemiology, University of Pittsburgh and the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania., Meng Z; Freenome Holdings Inc, Brisbane, California., Piscitello A; Freenome Holdings Inc, Brisbane, California., Sun CK; Freenome Holdings Inc, Brisbane, California., Xu C; Freenome Holdings Inc, Brisbane, California.; Now with CBX Consulting LLC, San Jose, California., Lin CJ; Freenome Holdings Inc, Brisbane, California., Lee LC; Freenome Holdings Inc, Brisbane, California., Baldo L; Freenome Holdings Inc, Brisbane, California.; Now with Beacon Therapeutics, Alachua, Florida., Levin TR; Kaiser Permanente Division of Research, Pleasanton, California.
Corporate Authors: PREEMPT CRC Investigators
Source: JAMA [JAMA] 2025 Jul 01; Vol. 334 (1), pp. 56-63.
Publication Type: Journal Article; Multicenter Study; Observational Study; Validation Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Shaukat+A%22">Shaukat A</searchLink>; NYU Grossman School of Medicine, New York, New York.; University of Minnesota Twin Cities, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Burke+CA%22">Burke CA</searchLink>; Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Chan+AT%22">Chan AT</searchLink>; Massachusetts General Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Grady+WM%22">Grady WM</searchLink>; Fred Hutchinson Cancer Center, Seattle, Washington.; University of Washington School of Medicine, Seattle.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; University of California, San Diego.<br /><searchLink fieldCode="AU" term="%22Katona+BW%22">Katona BW</searchLink>; University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Ladabaum+U%22">Ladabaum U</searchLink>; Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Liang+PS%22">Liang PS</searchLink>; NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Liu+JJ%22">Liu JJ</searchLink>; Morehouse School of Medicine, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Putcha+G%22">Putcha G</searchLink>; Freenome Holdings Inc, Brisbane, California.; Now with Precision Medicine and Diagnostics, Los Altos Hills, California.<br /><searchLink fieldCode="AU" term="%22Robertson+DJ%22">Robertson DJ</searchLink>; Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.<br /><searchLink fieldCode="AU" term="%22Schoen+RE%22">Schoen RE</searchLink>; Departments of Medicine and Epidemiology, University of Pittsburgh and the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Meng+Z%22">Meng Z</searchLink>; Freenome Holdings Inc, Brisbane, California.<br /><searchLink fieldCode="AU" term="%22Piscitello+A%22">Piscitello A</searchLink>; Freenome Holdings Inc, Brisbane, California.<br /><searchLink fieldCode="AU" term="%22Sun+CK%22">Sun CK</searchLink>; Freenome Holdings Inc, Brisbane, California.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Freenome Holdings Inc, Brisbane, California.; Now with CBX Consulting LLC, San Jose, California.<br /><searchLink fieldCode="AU" term="%22Lin+CJ%22">Lin CJ</searchLink>; Freenome Holdings Inc, Brisbane, California.<br /><searchLink fieldCode="AU" term="%22Lee+LC%22">Lee LC</searchLink>; Freenome Holdings Inc, Brisbane, California.<br /><searchLink fieldCode="AU" term="%22Baldo+L%22">Baldo L</searchLink>; Freenome Holdings Inc, Brisbane, California.; Now with Beacon Therapeutics, Alachua, Florida.<br /><searchLink fieldCode="AU" term="%22Levin+TR%22">Levin TR</searchLink>; Kaiser Permanente Division of Research, Pleasanton, California.
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  Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2025 Jul 01; Vol. 334 (1), pp. 56-63.
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        Value: 10.1001/jama.2025.7515
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              Text: 2025 Jul 01
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