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Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.

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Title: Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.
Authors: Marcucci M; Population Health Research Institute, Hamilton, Ontario, Canada; Clinical Epidemiology and Research Centre, Humanitas University & IRCCS Humanitas Research Hospital, Milan, Italy; and Department of Health Research Methods, McMaster University, Hamilton, Ontario, Canada (M.Marcucci)., Chan MTV; The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China (M.T.V.C.)., Painter TW; Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia (T.W.P.)., Efremov S; Saint Petersburg State University Hospital, Saint Petersburg, Russia (S.E.)., Aguado HJ; Trauma & Orthopaedic Surgery Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain (H.J.A.)., Astrakov SV; Department of Anesthesiology, Novosibirsk State University, Novosibirsk, Russia (S.V.A.)., Kleinlugtenbelt YV; Department of Orthopedic and Trauma Surgery, Deventer Ziekenhuis, Deventer, the Netherlands (Y.V.K.)., Patel A; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.)., Cata JP; MD Anderson Cancer Center, Houston, Texas (J.P.C.)., Amir M; Department of Surgery, Shifa International Hospital and Shifa Tameer-e-Millat University, Islamabad, Pakistan (M.A.)., Kirov M; Department of Anesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russia (M.K.)., Leslie K; Department of Critical Care Medicine, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia (K.L.)., Duceppe E; Population Health Research Institute, Hamilton, Ontario, Canada; and Department of Medicine, Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada (E.D.)., Borges FK; Population Health Research Institute, Hamilton, Ontario; Department of Health Research Methods, McMaster University, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (F.K.B., D.C.)., de Nadal M; Department of Anesthesiology and Intensive Care, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain (M.d.N.)., Tandon V; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.)., Landoni G; Department of Anesthesiology and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan; and Vita-Salute San Raffaele University, Milan, Italy (G.L.)., Likhvantsev VV; V. Negovsky Reanimatology Research Institute FRCC RR, Moscow, Russia (V.V.L.)., Lomivorotov V; Department of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Centre, Novosibirsk, Russia; and Department of Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania (V.L.)., Sessler DI; Center for Outcomes Research and Department of Anesthesiology, UTHealth, Houston, Texas (D.I.S.)., Martínez-Zapata MJ; Iberoamerican Cochrane Centre, Public Health and Clinical Epidemiology Service, Institut de Recerca Sant Pau, CIBERESP, Barcelona, Spain (M.J.M.-Z.)., Xavier D; St. John's Medical College, Bangalore, India (D.X.)., Fleischmann E; Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria (E.F.)., Wang CY; Department of Anesthesiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia (C.Y.W.)., Meyhoff CS; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark (C.S.M.)., Wittmann M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany (M.W.)., Torres D; Departamento de Epidemiología y Estudios en Salud, Universidad de Los Andes, Santiago, Chile (D.T.)., Highton D; Princess Alexandra Hospital, Woolloongabba, Queensland, Australia (D.H.)., Jacka M; Anesthesiology and Critical Care, University of Alberta, Edmonton, Alberta, Canada (M.J.)., B V; Nanjappa Hospital, Karnataka, India (V.B.)., Zarnke K; University of Calgary, Calgary, Alberta, Canada (K.Z.)., Sidhu RS; Sidhu Hospital Doraha Ludhiana, Ludhiana, India (R.S.S.)., Oriani G; IRCCS Galeazzi Sant'Ambrogio (OGSA), Site Istituto San Siro, Milan, Italy (G.O.)., Ayad S; Outcome Research Consortium, Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio (S.A.)., Minear S; Cleveland Clinic Florida, Weston, Florida (S.Minear)., Weaver TE; The Ohio State University Wexner Medical Center, Columbus, Ohio (T.E.W.)., Ruetzler K; Department of Anesthesiology and Intensive Care Medicine, Ordensklinikum Linz, Linz, Austria (K.R.)., Brusasco C; Anaesthesia and Intensive Care Medicine, Galliera Hospital, Genova, Italy (C.B.)., Parlow JL; Department of Anesthesiology and Perioperative Medicine, Queen's University and Kingston Health Sciences Centre, Kingston, Ontario, Canada (J.L.P., T.G.S.)., Maxwell E; Department of Anaesthesia, Auckland City Hospital, Auckland, New Zealand (E.M.)., Miller S; Wake Forest School of Medicine, Winston Salem, North Carolina (S.Miller)., Mrkobrada M; Department of Medicine, Western University, London, Ontario, Canada (M.Mrkobrada)., Bhatt KSC; Surat Institution, Surat, India (K.S.C.B.)., Rahate P; Rahate Surgical Hospital, Nagpur, India (P.R.)., Kowark A; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany; and University Hospital RWTH Aachen, Aachen, Germany (A.Kowark)., De Blasio G; IRCCS Galeazzi Orthopedic Institute, Milan, Italy (G.D.B.)., Ofori SN; Population Health Research Institute, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (S.N.O., M.K.W., M.S.)., Conen D; Population Health Research Institute, Hamilton, Ontario; Department of Health Research Methods, McMaster University, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (F.K.B., D.C.)., Srinathan S; Section of Thoracic Surgery, Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada (S.S.)., Szczeklik W; Centre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland (W.S.)., Jayaram R; Department of Anaesthetics, Clinical Neurosciences, University of Oxford, Oxford University Hospitals NHS Trust, Oxford, United Kingdom (R.J.)., Ellerkmann RK; Department of Anesthesiology, Klinikum Dortmund, University Witten-Herdecke, Dortmund, Germany (R.K.E.)., Momeni M; Cliniques Universitaires Saint-Luc, Brussels, Belgium (M.Momeni)., Copland I; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.)., Vincent J; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.)., Balasubramanian K; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.)., Li Z; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.)., Wang MK; Population Health Research Institute, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (S.N.O., M.K.W., M.S.)., Li D; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.)., McGillion MH; Population Health Research Institute, Hamilton, Ontario; and School of Nursing, McMaster University, Hamilton, Ontario, Canada (M.H.M.)., Kurz A; Outcome Research Consortium, Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio; and Department of General Anesthesiology, Emergency and Intensive Care Medicine, Medical University of Graz, Graz, Austria (A.Kurz)., Sharma M; Population Health Research Institute, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (S.N.O., M.K.W., M.S.)., Short TG; Department of Anesthesiology and Perioperative Medicine, Queen's University and Kingston Health Sciences Centre, Kingston, Ontario, Canada (J.L.P., T.G.S.)., Devereaux PJ; Population Health Research Institute, Hamilton, Ontario; and Department of Health Research Methods, McMaster University, Hamilton, Ontario, Canada (P.J.D.).
Corporate Authors: cogPOISE-3 Trial Investigators and Study Groups
Source: Annals of internal medicine [Ann Intern Med] 2025 Jul; Vol. 178 (7), pp. 909-920. Date of Electronic Publication: 2025 Jun 03.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: American College of Physicians--American Society of Internal Medicine Country of Publication: United States NLM ID: 0372351 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-3704 (Electronic) Linking ISSN: 00034819 NLM ISO Abbreviation: Ann Intern Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.
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  Data: <searchLink fieldCode="AU" term="%22Marcucci+M%22">Marcucci M</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada; Clinical Epidemiology and Research Centre, Humanitas University & IRCCS Humanitas Research Hospital, Milan, Italy; and Department of Health Research Methods, McMaster University, Hamilton, Ontario, Canada (M.Marcucci).<br /><searchLink fieldCode="AU" term="%22Chan+MTV%22">Chan MTV</searchLink>; The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China (M.T.V.C.).<br /><searchLink fieldCode="AU" term="%22Painter+TW%22">Painter TW</searchLink>; Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia (T.W.P.).<br /><searchLink fieldCode="AU" term="%22Efremov+S%22">Efremov S</searchLink>; Saint Petersburg State University Hospital, Saint Petersburg, Russia (S.E.).<br /><searchLink fieldCode="AU" term="%22Aguado+HJ%22">Aguado HJ</searchLink>; Trauma & Orthopaedic Surgery Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain (H.J.A.).<br /><searchLink fieldCode="AU" term="%22Astrakov+SV%22">Astrakov SV</searchLink>; Department of Anesthesiology, Novosibirsk State University, Novosibirsk, Russia (S.V.A.).<br /><searchLink fieldCode="AU" term="%22Kleinlugtenbelt+YV%22">Kleinlugtenbelt YV</searchLink>; Department of Orthopedic and Trauma Surgery, Deventer Ziekenhuis, Deventer, the Netherlands (Y.V.K.).<br /><searchLink fieldCode="AU" term="%22Patel+A%22">Patel A</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.).<br /><searchLink fieldCode="AU" term="%22Cata+JP%22">Cata JP</searchLink>; MD Anderson Cancer Center, Houston, Texas (J.P.C.).<br /><searchLink fieldCode="AU" term="%22Amir+M%22">Amir M</searchLink>; Department of Surgery, Shifa International Hospital and Shifa Tameer-e-Millat University, Islamabad, Pakistan (M.A.).<br /><searchLink fieldCode="AU" term="%22Kirov+M%22">Kirov M</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russia (M.K.).<br /><searchLink fieldCode="AU" term="%22Leslie+K%22">Leslie K</searchLink>; Department of Critical Care Medicine, Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia (K.L.).<br /><searchLink fieldCode="AU" term="%22Duceppe+E%22">Duceppe E</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada; and Department of Medicine, Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada (E.D.).<br /><searchLink fieldCode="AU" term="%22Borges+FK%22">Borges FK</searchLink>; Population Health Research Institute, Hamilton, Ontario; Department of Health Research Methods, McMaster University, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (F.K.B., D.C.).<br /><searchLink fieldCode="AU" term="%22de+Nadal+M%22">de Nadal M</searchLink>; Department of Anesthesiology and Intensive Care, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain (M.d.N.).<br /><searchLink fieldCode="AU" term="%22Tandon+V%22">Tandon V</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.).<br /><searchLink fieldCode="AU" term="%22Landoni+G%22">Landoni G</searchLink>; Department of Anesthesiology and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan; and Vita-Salute San Raffaele University, Milan, Italy (G.L.).<br /><searchLink fieldCode="AU" term="%22Likhvantsev+VV%22">Likhvantsev VV</searchLink>; V. 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Hershey Medical Center, Hershey, Pennsylvania (V.L.).<br /><searchLink fieldCode="AU" term="%22Sessler+DI%22">Sessler DI</searchLink>; Center for Outcomes Research and Department of Anesthesiology, UTHealth, Houston, Texas (D.I.S.).<br /><searchLink fieldCode="AU" term="%22Martínez-Zapata+MJ%22">Martínez-Zapata MJ</searchLink>; Iberoamerican Cochrane Centre, Public Health and Clinical Epidemiology Service, Institut de Recerca Sant Pau, CIBERESP, Barcelona, Spain (M.J.M.-Z.).<br /><searchLink fieldCode="AU" term="%22Xavier+D%22">Xavier D</searchLink>; St. John's Medical College, Bangalore, India (D.X.).<br /><searchLink fieldCode="AU" term="%22Fleischmann+E%22">Fleischmann E</searchLink>; Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria (E.F.).<br /><searchLink fieldCode="AU" term="%22Wang+CY%22">Wang CY</searchLink>; Department of Anesthesiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia (C.Y.W.).<br /><searchLink fieldCode="AU" term="%22Meyhoff+CS%22">Meyhoff CS</searchLink>; 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Anaesthesia and Intensive Care Medicine, Galliera Hospital, Genova, Italy (C.B.).<br /><searchLink fieldCode="AU" term="%22Parlow+JL%22">Parlow JL</searchLink>; Department of Anesthesiology and Perioperative Medicine, Queen's University and Kingston Health Sciences Centre, Kingston, Ontario, Canada (J.L.P., T.G.S.).<br /><searchLink fieldCode="AU" term="%22Maxwell+E%22">Maxwell E</searchLink>; Department of Anaesthesia, Auckland City Hospital, Auckland, New Zealand (E.M.).<br /><searchLink fieldCode="AU" term="%22Miller+S%22">Miller S</searchLink>; Wake Forest School of Medicine, Winston Salem, North Carolina (S.Miller).<br /><searchLink fieldCode="AU" term="%22Mrkobrada+M%22">Mrkobrada M</searchLink>; Department of Medicine, Western University, London, Ontario, Canada (M.Mrkobrada).<br /><searchLink fieldCode="AU" term="%22Bhatt+KSC%22">Bhatt KSC</searchLink>; Surat Institution, Surat, India (K.S.C.B.).<br /><searchLink fieldCode="AU" term="%22Rahate+P%22">Rahate P</searchLink>; Rahate Surgical Hospital, Nagpur, India (P.R.).<br /><searchLink fieldCode="AU" term="%22Kowark+A%22">Kowark A</searchLink>; 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Centre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland (W.S.).<br /><searchLink fieldCode="AU" term="%22Jayaram+R%22">Jayaram R</searchLink>; Department of Anaesthetics, Clinical Neurosciences, University of Oxford, Oxford University Hospitals NHS Trust, Oxford, United Kingdom (R.J.).<br /><searchLink fieldCode="AU" term="%22Ellerkmann+RK%22">Ellerkmann RK</searchLink>; Department of Anesthesiology, Klinikum Dortmund, University Witten-Herdecke, Dortmund, Germany (R.K.E.).<br /><searchLink fieldCode="AU" term="%22Momeni+M%22">Momeni M</searchLink>; Cliniques Universitaires Saint-Luc, Brussels, Belgium (M.Momeni).<br /><searchLink fieldCode="AU" term="%22Copland+I%22">Copland I</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.).<br /><searchLink fieldCode="AU" term="%22Vincent+J%22">Vincent J</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.).<br /><searchLink fieldCode="AU" term="%22Balasubramanian+K%22">Balasubramanian K</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.).<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Population Health Research Institute, Hamilton, Ontario, Canada (I.C., J.V., K.B., Z.L.).<br /><searchLink fieldCode="AU" term="%22Wang+MK%22">Wang MK</searchLink>; Population Health Research Institute, Hamilton, Ontario; and Department of Medicine, McMaster University, Hamilton, Ontario, Canada (S.N.O., M.K.W., M.S.).<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Department of Medicine, McMaster University, Hamilton, Ontario, Canada (A.P., V.T., D.L.).<br /><searchLink fieldCode="AU" term="%22McGillion+MH%22">McGillion MH</searchLink>; Population Health Research Institute, Hamilton, Ontario; and School of Nursing, McMaster University, Hamilton, Ontario, Canada (M.H.M.).<br /><searchLink fieldCode="AU" term="%22Kurz+A%22">Kurz A</searchLink>; Outcome Research Consortium, Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio; 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  Data: <searchLink fieldCode="JN" term="%220372351%22">Annals of internal medicine</searchLink> [Ann Intern Med] 2025 Jul; Vol. 178 (7), pp. 909-920. <i>Date of Electronic Publication: </i>2025 Jun 03.
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      – TitleFull: Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.
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          Dates:
            – D: 01
              M: 07
              Text: 2025 Jul
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1539-3704
          Numbering:
            – Type: volume
              Value: 178
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Annals of internal medicine
              Type: main
ResultId 1