Late-Life Short-Term Dietary Restriction Improves Intestinal Stem Cell Function and Alters Intestinal Stem Cell Deoxyribonucleic Acid Methylation in Mice.

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Title: Late-Life Short-Term Dietary Restriction Improves Intestinal Stem Cell Function and Alters Intestinal Stem Cell Deoxyribonucleic Acid Methylation in Mice.
Authors: Kurup K; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States., Chan M; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Harold Hamm Diabetes Center, Oklahoma City, OK, United States., Moore E; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States., Ranjo-Bishop M; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States., Pham K; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, United States., Stanford DR; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, United States., Freeman WM; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, United States., Unnikrishnan A; Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States; Harold Hamm Diabetes Center, Oklahoma City, OK, United States; Oklahoma Center for Geroscience and Brain Aging, Oklahoma City, OK, United States. Electronic address: archana-unnikrishnan@ouhsc.edu.
Source: The Journal of nutrition [J Nutr] 2025 Aug; Vol. 155 (8), pp. 2568-2581. Date of Electronic Publication: 2025 May 31.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0404243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-6100 (Electronic) Linking ISSN: 00223166 NLM ISO Abbreviation: J Nutr Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1541-6100
DOI:10.1016/j.tjnut.2025.05.044