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A multi-ancestry genetic reference for the Quebec population.

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Title: A multi-ancestry genetic reference for the Quebec population.
Authors: McClelland P; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Femerling G; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Laflamme R; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada., Mejia-Garcia A; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Dehkordi MS; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Xiao H; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Diaz-Papkovich A; Quantitative Life Sciences, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.; Data Science Institute, Brown University, 164 Angell Street, Providence, Rhode Island, 02906, USA., Pelletier J; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Grenier JC; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada., Lo KS; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada., Anderson-Trocmé L; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Bellavance J; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada., Chapdelaine V; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Gagnon G; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.; Department of Medicine, Université Laval, 1050 Av. de la Médecine, Quebec, Quebec, G1V 0A6, Canada., Mori A; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada., Martinez G; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Mohler K; Department of Pediatrics, Medical Genetics, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Internal Medicine, Medical Genetics, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.; CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., de Malliard T; CARTaGENE, CHU Sainte-Justine Research Center, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., Labbé C; CARTaGENE, CHU Sainte-Justine Research Center, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., Labrecque M; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada., Montpetit A; Génome Québec, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., Spiegelman D; CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., Rouleau GA; Montreal Neurological Institute-Hospital, Department of Neurology and Neurosurgery, 3801 Rue University, Montreal, Quebec, H3A 2B4, Canada., Théroux JF; Génome Québec, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada., Zhou H; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA., Girard SL; Fundamental Sciences, Université du Québec à Chicoutimi, 555, Boulevard de l'Université, Chicoutimi, Quebec, G7H3P6, Canada., Hussin JG; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Mila Quebec AI Institute, 6666 Saint-Urbain Street, Montreal, Quebec, H2S 3H1, Canada., Laberge AM; Department of Pediatrics, Medical Genetics, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.; Department of Social and Preventive Medicine, École de Santé Publique de l'Université de Montréal, 7101 Avenue Parc, Montreal, Quebec, H3N 1X9, Canada., Bhérer C; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Tetreault M; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.; Department of Neurosciences, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada., Gagliano Taliun SA; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Neurosciences, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada., Taliun D; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Gravel S; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada., Lettre G; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 May 16. Date of Electronic Publication: 2025 May 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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IllustrationInfo
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  Data: A multi-ancestry genetic reference for the Quebec population.
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  Data: <searchLink fieldCode="AU" term="%22McClelland+P%22">McClelland P</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Femerling+G%22">Femerling G</searchLink>; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Laflamme+R%22">Laflamme R</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.<br /><searchLink fieldCode="AU" term="%22Mejia-Garcia+A%22">Mejia-Garcia A</searchLink>; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Dehkordi+MS%22">Dehkordi MS</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Diaz-Papkovich+A%22">Diaz-Papkovich A</searchLink>; Quantitative Life Sciences, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.; Data Science Institute, Brown University, 164 Angell Street, Providence, Rhode Island, 02906, USA.<br /><searchLink fieldCode="AU" term="%22Pelletier+J%22">Pelletier J</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Grenier+JC%22">Grenier JC</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.<br /><searchLink fieldCode="AU" term="%22Lo+KS%22">Lo KS</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.<br /><searchLink fieldCode="AU" term="%22Anderson-Trocmé+L%22">Anderson-Trocmé L</searchLink>; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Bellavance+J%22">Bellavance J</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.<br /><searchLink fieldCode="AU" term="%22Chapdelaine+V%22">Chapdelaine V</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Gagnon+G%22">Gagnon G</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.; Department of Medicine, Université Laval, 1050 Av. de la Médecine, Quebec, Quebec, G1V 0A6, Canada.<br /><searchLink fieldCode="AU" term="%22Mori+A%22">Mori A</searchLink>; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.<br /><searchLink fieldCode="AU" term="%22Martinez+G%22">Martinez G</searchLink>; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Mohler+K%22">Mohler K</searchLink>; Department of Pediatrics, Medical Genetics, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Internal Medicine, Medical Genetics, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.; CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.<br /><searchLink fieldCode="AU" term="%22de+Malliard+T%22">de Malliard T</searchLink>; CARTaGENE, CHU Sainte-Justine Research Center, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Labbé+C%22">Labbé C</searchLink>; CARTaGENE, CHU Sainte-Justine Research Center, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Labrecque+M%22">Labrecque M</searchLink>; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.<br /><searchLink fieldCode="AU" term="%22Montpetit+A%22">Montpetit A</searchLink>; Génome Québec, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.<br /><searchLink fieldCode="AU" term="%22Spiegelman+D%22">Spiegelman D</searchLink>; 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Chan School of Public Health, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Girard+SL%22">Girard SL</searchLink>; Fundamental Sciences, Université du Québec à Chicoutimi, 555, Boulevard de l'Université, Chicoutimi, Quebec, G7H3P6, Canada.<br /><searchLink fieldCode="AU" term="%22Hussin+JG%22">Hussin JG</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Biochemistry and Molecular Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Mila Quebec AI Institute, 6666 Saint-Urbain Street, Montreal, Quebec, H2S 3H1, Canada.<br /><searchLink fieldCode="AU" term="%22Laberge+AM%22">Laberge AM</searchLink>; Department of Pediatrics, Medical Genetics, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; CHU Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec, H3T1C5, Canada.; Department of Social and Preventive Medicine, École de Santé Publique de l'Université de Montréal, 7101 Avenue Parc, Montreal, Quebec, H3N 1X9, Canada.<br /><searchLink fieldCode="AU" term="%22Bhérer+C%22">Bhérer C</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Tetreault+M%22">Tetreault M</searchLink>; Centre de recherche du Centre Hospitalier de l'Université de Montréal, 900 rue St-Denis, Montreal, Quebec, H2X 0A9, Canada.; Department of Neurosciences, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.<br /><searchLink fieldCode="AU" term="%22Gagliano+Taliun+SA%22">Gagliano Taliun SA</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.; Department of Neurosciences, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.<br /><searchLink fieldCode="AU" term="%22Taliun+D%22">Taliun D</searchLink>; Department of Human Genetics, McGill CERC Program in Genomic Medicine, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Gravel+S%22">Gravel S</searchLink>; Department of Human Genetics, Victor Phillip Dahdaleh Institute of Genomic Medicine at McGill University, 740 Av. du Docteur-Penfield, Montreal, Quebec, H3A 0G1, Canada.<br /><searchLink fieldCode="AU" term="%22Lettre+G%22">Lettre G</searchLink>; Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, H1T 1C8, Canada.; Department of Medicine, Université de Montréal, 2900 Boulevard Edouard-Montpetit, Montreal, Quebec, H3C 3J7, Canada.
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