Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study.

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Title: Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study.
Authors: Morales DR; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, U.K., Bu F; Department of Biostatistics, University of Michigan at Ann Arbor, Ann Arbor, MI., Viernes B; Veterans Affairs Informatics and Computing Infrastructure Department of Veterans Affairs, Salt Lake City, UT.; Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT., DuVall SL; Veterans Affairs Informatics and Computing Infrastructure Department of Veterans Affairs, Salt Lake City, UT.; Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT., Matheny ME; Tennessee Valley Healthcare System, Veterans Affairs Medical Center, Nashville, TN.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN., Simon KR; Tennessee Valley Healthcare System, Veterans Affairs Medical Center, Nashville, TN.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN., Falconer T; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY., Richter LR; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY.; Division of Pediatric Endocrinology, Diabetes, and Metabolism, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY., Ostropolets A; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY., Lau WCY; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Hong Kong, China.; Research Department of Practice and Policy, School of Pharmacy, University College London, London, U.K.; Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, U.K., Man KKC; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Hong Kong, China.; Research Department of Practice and Policy, School of Pharmacy, University College London, London, U.K.; Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, U.K., Chattopadhyay S; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA., Mathioudakis N; Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD., Minty E; Faculty of Medicine, O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada., Nishimura A; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD., Sun F; Department of Epidemiology and Biostatistics, Peking University, Beijing, China., Yin C; DTA&AI, Real World Solutions, IQVIA, Durham, NC., Seager SL; DTA&AI, Real World Solutions, IQVIA, Durham, NC., Chai Y; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Zhou JJ; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA., Lu Y; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT., Reyes C; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain., Pistillo A; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain., Duarte-Salles T; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain., Blacketer C; Observational Health Data Analytics, Janssen Research and Development, LLC, Titusville, NJ., Schuemie MJ; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Epidemiology, Office of the Chief Medical Officer, Johnson & Johnson, Titusville, NJ., Ryan PB; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY.; Epidemiology, Office of the Chief Medical Officer, Johnson & Johnson, Titusville, NJ., Krumholz HM; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT., Hripcsak G; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY., Khera R; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.; Section of Health Informatics, Department of Biostatistics, Yale School of Public Health, New Haven, CT., Suchard MA; Veterans Affairs Informatics and Computing Infrastructure Department of Veterans Affairs, Salt Lake City, UT.; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Source: Diabetes care [Diabetes Care] 2025 Aug 01; Vol. 48 (8), pp. 1386-1394.
Publication Type: Journal Article
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE
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  Data: Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study.
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Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Hong Kong, China.; Research Department of Practice and Policy, School of Pharmacy, University College London, London, U.K.; Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, U.K.<br /><searchLink fieldCode="AU" term="%22Man+KKC%22">Man KKC</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Hong Kong, China.; Research Department of Practice and Policy, School of Pharmacy, University College London, London, U.K.; Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, U.K.<br /><searchLink fieldCode="AU" term="%22Chattopadhyay+S%22">Chattopadhyay S</searchLink>; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Mathioudakis+N%22">Mathioudakis N</searchLink>; Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Minty+E%22">Minty E</searchLink>; Faculty of Medicine, O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Nishimura+A%22">Nishimura A</searchLink>; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Sun+F%22">Sun F</searchLink>; Department of Epidemiology and Biostatistics, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yin+C%22">Yin C</searchLink>; DTA&AI, Real World Solutions, IQVIA, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Seager+SL%22">Seager SL</searchLink>; DTA&AI, Real World Solutions, IQVIA, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Chai+Y%22">Chai Y</searchLink>; Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Zhou+JJ%22">Zhou JJ</searchLink>; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT.<br /><searchLink fieldCode="AU" term="%22Reyes+C%22">Reyes C</searchLink>; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pistillo+A%22">Pistillo A</searchLink>; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Duarte-Salles+T%22">Duarte-Salles T</searchLink>; Real-World Epidemiology Research Group, Fundaci Institut Universitari per a la recerca a l'Atenci Primria de Salut Jordi Gol i Gurina, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blacketer+C%22">Blacketer C</searchLink>; Observational Health Data Analytics, Janssen Research and Development, LLC, Titusville, NJ.<br /><searchLink fieldCode="AU" term="%22Schuemie+MJ%22">Schuemie MJ</searchLink>; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Epidemiology, Office of the Chief Medical Officer, Johnson & Johnson, Titusville, NJ.<br /><searchLink fieldCode="AU" term="%22Ryan+PB%22">Ryan PB</searchLink>; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY.; Epidemiology, Office of the Chief Medical Officer, Johnson & Johnson, Titusville, NJ.<br /><searchLink fieldCode="AU" term="%22Krumholz+HM%22">Krumholz HM</searchLink>; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT.<br /><searchLink fieldCode="AU" term="%22Hripcsak+G%22">Hripcsak G</searchLink>; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Khera+R%22">Khera R</searchLink>; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT.; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.; Section of Health Informatics, Department of Biostatistics, Yale School of Public Health, New Haven, CT.<br /><searchLink fieldCode="AU" term="%22Suchard+MA%22">Suchard MA</searchLink>; Veterans Affairs Informatics and Computing Infrastructure Department of Veterans Affairs, Salt Lake City, UT.; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA.; Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
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